Results 291 to 300 of about 1,128,759 (377)

Delivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications

Advanced Science, EarlyView.
This review focuses on the immunomodulatory mechanisms of molecular hydrogen, the recent detection methods, and the classification advanced molecular hydrogen delivery materials. It provides a detailed description of their applications in areas such as arthritis, chronic wounds, cardiovascular injury, tumors, and bacterial infections, aiming to enhance
Gangfeng Li, Hannan Cui, Ruixiao Fan, Guming Liu, Zishuo Hou, Yibo Zhang, Xuanming Che, Tengjiao Wang, Hongbo Wei, Peng Li   +9 more
wiley   +1 more source

The Role of Vitamin D in Inflammatory Bowel Diseases: From Deficiency to Targeted Therapeutics and Precise Nutrition Strategies. [PDF]

Nutrients
Dell'Anna G, Fanizzi F, Zilli A, Furfaro F, Solitano V, Parigi TL, Ciliberto A, Fanizza J, Mandarino FV, Fuccio L, Facciorusso A, Donatelli G, Allocca M, Massironi S, Annese V, Peyrin-Biroulet L, Danese S, D'Amico F.   +17 more
europepmc   +1 more source

Peripheral Blood Mononuclear Cells From Patients With Inflammatory Bowel Disease Exhibit Normal Function in the Allogeneic and Autologous Mixed Leukocyte Reaction and Cell-Mediated Lympholysis

, 1984
Richard P. MacDermott, M. Janice Bragdon, R. Donogene Thurmond   +2 more
openalex   +1 more source

Novel Antimicrobial Protein Fibroblast Growth Factor 8 Accelerates Skin Wound Healing via Directly Inhibiting Bacteria and Activating Glycolysis

Advanced Science, EarlyView.
Wound infections induce gcFGF8a expression, which subsequently executes direct antimicrobial activity to suppress local infection while simultaneously activating the FGFR4‐mediated ERK/AKT‐mTOR signaling cascade, thereby upregulating HIF1α and enhancing glycolysis. These coordinated actions synergistically promote tissue repair by eliminating pathogens
Ya‐Zhen Hu, Ting Wang, Chang‐Song Wu, Jie Wang, Xue‐Qing Han, Yong‐An Zhang, Xu‐Jie Zhang   +6 more
wiley   +1 more source

Relevance of Glucagon-Like Peptide 1 (GLP-1) in Inflammatory Bowel Diseases: A Narrative Review. [PDF]

Curr Issues Mol Biol
Gravina AG, Pellegrino R, Izzo M, De Costanzo I, Imperio G, Landa F, Tambaro A, Federico A.   +7 more
europepmc   +1 more source

Use of Methotrexate in the Treatment of Inflammatory Bowel Diseases

Inflammatory Bowel Diseases, 2016
H. Herfarth, M. Kappelman, M. Long, K. Isaacs   +3 more
semanticscholar   +1 more source

ACSS2‐Mediated Histone H4 Lysine 12 Crotonylation (H4K12cr) Alleviates Colitis via Enhancing Transcription of CLDN7

Advanced Science, EarlyView.
Histone lysine crotonylation (Kcr) is a highly conserved posttranslational modification implicated with crucial biological processes. This study reveals that ACSS2‐mediated H4K12cr upregulated CLDN7 transcription to strengthen intestinal epithelial barrier.
Ming Yuan, Shaopeng Chen, Zhensen Lin, Runfeng Yu, Kang Chao, Shubiao Ye, Qing Li, Haoxian Ke, Chi Zhang, Junfeng Huang, Guanzhan Liang, Tuo Hu, Xiang Gao, Ping Lan, Xianrui Wu   +14 more
wiley   +1 more source

Proteomic Profiling of Extracellular Vesicles in Inflammatory Bowel Diseases. [PDF]

Int J Mol Sci
Baldán-Martín M, Azkargorta M, Lapitz A, Ortega Moreno L, Iloro I, Fernández-Tomé S, Arbelaiz A, Escobes I, Marín AC, Bernardo D, Bujanda L, Bañales JM, Elortza F, Gisbert JP, Chaparro M.   +14 more
europepmc   +1 more source

A Possible mechanism of action of sulfasalazine and 5-aminosalicylic acid in inflammatory bowel diseases: Interaction with oxygen free radicals

, 1985
Piero Del Soldato, Massimo Campieri, C. Brignola, Gabriele Bazzocchi, Paolo Gionchetti, Giorgio Assuero Lanfranchi, Michiko Tamba   +6 more
openalex   +1 more source

Intestinal Epithelial‐Derived USP13 Alleviates Colonic Inflammation by Suppressing GRP78‐mediated Endoplasmic Reticulum Stress

Advanced Science, EarlyView.
USP13 deficiency in intestinal epithelial cells aggravates DSS‐induced colitis by enhancing ER stress and apoptosis. USP13 interacts with GRP78 and reduces its K63‐linked ubiquitination to alleviate epithelial injury. Restoring USP13 expression or targeting the USP13‐GRP78 axis may represent a promising strategy for treating inflammatory bowel disease ...
Chenchen Qian, Chenghong Hu, Yong Xu, Wentao Xu, Zhe Wang, Wan Gan, Weiyang Tang, Lijiang Huang, Aleksandr V. Samorodov, Yi Wang   +9 more
wiley   +1 more source