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Idiopathic inflammatory myopathies [PDF]

Nature Reviews Disease Primers, 2021
Idiopathic inflammatory myopathies (IIM), also known as myositis, are a heterogeneous group of autoimmune disorders with varying clinical manifestations, treatment responses and prognoses. Muscle weakness is usually the classical clinical manifestation but other organs can be affected, including the skin, joints, lungs, heart and gastrointestinal tract,
Ingrid E Lundberg, Manabu Fujimoto, Jiri Vencovsky   +2 more
exaly   +6 more sources

Concentric macro EMG role in electrodiagnostic evaluation of inflammatory myopathies [PDF]

European Journal of Translational Myology
Background: Inflammatory myopathies (IM) encompass a diverse group of systemic autoimmune muscle disorders, not easy to diagnose. Concentric-macro EMG is supposed to reflect electrical activity of the entire motor unit.
Eman ElZamarany, Ayat Allah Farouk, Lamia Afifi, Sandra Ahmed, Eman Ashraf, Eman Attia, Marwa Shalaby   +6 more
doaj   +2 more sources

Inflammasomes and idiopathic inflammatory myopathies [PDF]

Frontiers in Immunology
Idiopathic inflammatory myopathies (IIM) are a group of systemic autoimmune diseases characterized by muscle weakness and elevated serum creatine kinase levels.
Rui Sun, Jiyan Chu, Jiyan Chu, Ping Li
doaj   +2 more sources

Biomarkers in Inflammatory Myopathies—An Expanded Definition [PDF]

Frontiers in Neurology, 2019
Biomarkers as parameters of pathophysiological conditions can be of outmost relevance for inflammatory myopathies. They are particularly warranted to inform about diagnostic, prognostic, and therapeutic questions.
Olivier Benveniste, Hans-Hilmar Goebel, Hans-Hilmar Goebel, Werner Stenzel   +3 more
doaj   +4 more sources

Cardiac Involvement in Idiopathic Inflammatory Myopathies [PDF]

Journal of Inflammation Research
Hongji Zhu,1,2,* Runzhao Li,1,2,* Hongxia Tan,1,* Tangdan Ding,1,2 Ying Yuan,3 Zhihua Wen,4 Jijun Zhao,5 Min Liu,1 Qiong Shi,1 Liubing Li1 1Department of Laboratory Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou ...
Zhu H, Li R, Tan H, Ding T, Yuan Y, Wen Z, Zhao J, Liu M, Shi Q, Li L   +9 more
doaj   +2 more sources

G-Protein-Coupled Estrogen Receptor (GPER) in Inflammatory Myopathies [PDF]

Neurology International
Background/Objectives: Given the multifaceted role of estrogen hormones in skeletal muscle pathophysiology and their well-established immunomodulatory properties, this study aimed to characterize the expression of the G-protein-coupled estrogen receptor (
Delia Righi, Diego Lopergolo, Nila Volpi, Daniela Franci, Paola Lorenzoni, Margherita Aglianò, Gianna Berti, Carlo Manco, Nicola De Stefano, Federica Ginanneschi   +9 more
doaj   +2 more sources

The inflammatory pathology of dysferlinopathy is distinct from calpainopathy, Becker muscular dystrophy, and inflammatory myopathies

Acta Neuropathologica Communications, 2022
The descriptions of muscle pathology in dysferlinopathy patients have classically included an inflammatory infiltrate that can mimic inflammatory myopathies.
Nicole Becker, Steven A. Moore, Karra A. Jones   +2 more
doaj   +1 more source

Optimizing Cardiac Assessment in Idiopathic Inflammatory Myopathies [PDF]

Annals of Indian Academy of Neurology
Sruthi S Nair
doaj   +2 more sources

Idiopathic Inflammatory Myopathies [PDF]

Seminars in Neurology, 2009
The idiopathic inflammatory myopathies are a group of rare disorders including polymyositis (PM), dermatomyositis (DM), and autoimmune necrotizing myopathies (NMs). The idiopathic inflammatory myopathies share many similarities. They present acutely, subacutely, or chronically with marked proximal and symmetric muscle weakness, except for associated ...
Mazen M, Dimachkie, Richard J, Barohn
openaire   +6 more sources

Biological Therapies in Inflammatory Myopathies

Rambam Maimonides Medical Journal, 2023
Idiopathic inflammatory myopathies (IIM) are a rare group of disorders that feature progressive immune-mediated skeletal muscle destruction along with skin, lung, and joint involvement.
Abd El Haleem Natour, Shaye Kivity
doaj   +1 more source