Results 11 to 20 of about 1,609,796 (235)

G-Protein-Coupled Estrogen Receptor (GPER) in Inflammatory Myopathies [PDF]

open access: yesNeurology International
Background/Objectives: Given the multifaceted role of estrogen hormones in skeletal muscle pathophysiology and their well-established immunomodulatory properties, this study aimed to characterize the expression of the G-protein-coupled estrogen receptor (
Delia Righi   +9 more
doaj   +2 more sources

Biomarkers in Inflammatory Myopathies—An Expanded Definition

open access: yesFrontiers in Neurology, 2019
Biomarkers as parameters of pathophysiological conditions can be of outmost relevance for inflammatory myopathies. They are particularly warranted to inform about diagnostic, prognostic, and therapeutic questions.
Olivier Benveniste   +3 more
doaj   +2 more sources

Cardiovascular manifestations in idiopathic inflammatory myopathies

open access: yesClinical Rheumatology, 2023
Cardiovascular involvement in idiopathic inflammatory myopathies (IIM) is an understudied area which is gaining increasing recognition in recent times.
Meera Shah, S. Shinjo, J. Day, L. Gupta
semanticscholar   +1 more source

Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies

open access: yesNature Communications, 2022
Muscle cell death in polymyositis is induced by CD8 + cytotoxic T lymphocytes. We hypothesized that the injured muscle fibers release pro-inflammatory molecules, which would further accelerate CD8 + cytotoxic T lymphocytes-induced muscle injury, and ...
M. Kamiya   +9 more
semanticscholar   +1 more source

Biological Therapies in Inflammatory Myopathies

open access: yesRambam Maimonides Medical Journal, 2023
Idiopathic inflammatory myopathies (IIM) are a rare group of disorders that feature progressive immune-mediated skeletal muscle destruction along with skin, lung, and joint involvement.
Abd El Haleem Natour, Shaye Kivity
doaj   +1 more source

Idiopathic Inflammatory Myopathies [PDF]

open access: yesSeminars in Neurology, 2009
The idiopathic inflammatory myopathies are a group of rare disorders including polymyositis (PM), dermatomyositis (DM), and autoimmune necrotizing myopathies (NMs). The idiopathic inflammatory myopathies share many similarities. They present acutely, subacutely, or chronically with marked proximal and symmetric muscle weakness, except for associated ...
Mazen M, Dimachkie, Richard J, Barohn
openaire   +6 more sources

MRI and muscle imaging for idiopathic inflammatory myopathies

open access: yesBrain Pathology, 2021
Although idiopathic inflammatory myopathies (IIM) are a heterogeneous group of diseases nearly all patients display muscle inflammation. Originally, muscle biopsy was considered as the gold standard for IIM diagnosis.
Samuel Malartre   +6 more
semanticscholar   +1 more source

Idiopathic Inflammatory Myopathies [PDF]

open access: yesNeurologic Clinics, 2014
The idiopathic inflammatory myopathies (IIM) consist of rare heterogeneous autoimmune disorders that present with marked proximal and symmetric muscle weakness, except for distal and asymmetric weakness in inclusion body myositis. Despite many similarities, the IIM are fairly heterogeneous from the histopathologic and pathogenetic standpoints, and also
Mazen M, Dimachkie   +2 more
openaire   +5 more sources

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