Results 291 to 300 of about 1,587,143 (318)

Defining cardiac involvement in idiopathic inflammatory myopathies: a systematic review.

Rheumatology, 2021
OBJECTIVE Recent advances in cardiac magnetic resonance imaging (CMR) and other diagnostic techniques have made it easier to identify subclinical cardiac inflammation and dysfunction in the idiopathic inflammatory myopathies (IIM).
J. Fairley, I. Wicks, S. Peters, J. Day
semanticscholar   +1 more source

Role of MRI in idiopathic inflammatory myopathies: a review article

Acta Radiologica, 2021
Idiopathic inflammatory myopathies are a rare heterogeneous group of chronic, autoimmune conditions characterized by the slow, progressive weakness of the skeletal muscles and inflammatory infiltrates in the muscle tissue.
K. Pilania, B. Jankharia
semanticscholar   +1 more source

Inflammatory myopathies: update on diagnosis, pathogenesis and therapies, and COVID-19-related implications

Acta myologica, 2020
The inflammatory myopathies constitute a heterogeneous group of acquired myopathies that have in common the presence of endomysial inflammation. Based on steadily evolved clinical, histological and immunopathological features and some autoantibody ...
M. Dalakas
semanticscholar   +1 more source

Proinflammatory Histidyl–Transfer RNA Synthetase–Specific CD4+ T Cells in the Blood and Lungs of Patients With Idiopathic Inflammatory Myopathies

Arthritis & Rheumatology, 2020
Autoantibodies targeting histidyl–transfer RNA synthetase (HisRS; anti–Jo‐1) are common in the idiopathic inflammatory myopathies (IIMs) and antisynthetase syndrome.
A. Galindo-Feria, I. Albrecht, C. Fernandes-Cerqueira, A. Notarnicola, E. James, J. Herrath, M. Dastmalchi, T. Sandalova, L. Rönnblom, P. Jakobsson, M. Fathi, A. Achour, J. Grunewald, V. Malmström, I. Lundberg   +14 more
semanticscholar   +1 more source

Nonimmune mechanisms in idiopathic inflammatory myopathies

Current Opinion in Rheumatology, 2020
Purpose of review This review encompasses the main novelties regarding nonimmune mechanisms implicated in the pathogenesis of idiopathic inflammatory myopathies (IIM). Recent findings In recent years, growing data support a role for endoplasmic-reticulum
M. Loredo Martinez, S. Zampieri, C. Franco, A. Ghirardello, A. Doria, M. Gatto   +5 more
semanticscholar   +1 more source

Accumulation of autophagosome cargo protein p62 is common in idiopathic inflammatory myopathies.

Clinical and Experimental Rheumatology, 2020
OBJECTIVES The subsarcolemmal accumulation of p62 aggregates in myofibres has been proposed to be characteristic of sporadic inclusion body myositis (sIBM).
J. Milisenda, I. Pinal-Fernández, T. Lloyd, J. Grau, F. Miller, A. Selva-O’Callaghan, L. Christopher‐Stine, W. Stenzel, A. Mammen, A. Corse   +9 more
semanticscholar   +1 more source

Comparison of autoantibody specificities tested by a line blot assay and immunoprecipitation-based algorithm in patients with idiopathic inflammatory myopathies

Annals of the Rheumatic Diseases, 2019
More than 15 autoantibodies have been identified in patients with idiopathic inflammatory myopathies (IIM). Most of them are specific to patients with IIM and therefore called myositis-specific autoantibodies (MSA).1 There is no standardised approach of ...
F. Espinosa-Ortega, M. Holmqvist, H. Alexanderson, H. Storfors, T. Mimori, I. Lundberg, J. Rönnelid   +6 more
semanticscholar   +1 more source

Inflammatory myopathies

Oxford Textbook of Medicine, 2020
The idiopathic inflammatory myopathies are a heterogenous group of disorders characterized by muscle weakness, inflammation in muscle tissue, and with frequent extramuscular involvement. Autoantibodies are common, supporting the notion of these disorders
I. Lundberg, H. Chinoy, R. Cooper
semanticscholar   +1 more source

Classification of idiopathic inflammatory myopathies: pathology perspectives.

Current Opinion in Neurology, 2019
PURPOSE OF REVIEW Idiopathic inflammatory myopathies (IIMs) are rare diseases with heterogenous clinicopathological features. In recent years, new classification systems considering various combinations of clinical, serological, and pathological ...
J. Tanboon, I. Nishino
semanticscholar   +1 more source

Interferon-signature in idiopathic inflammatory myopathies.

Current Opinion in Rheumatology, 2019
PURPOSE OF REVIEW The present review describes the interferon (IFN)-signature currently emerging as a tool for the diagnosis of idiopathic inflammatory myopathies (IIMs), and aims at presenting the interests and limitations of this recent tool for the ...
L. Gallay, G. Mouchiroud, B. Chazaud
semanticscholar   +1 more source