Results 31 to 40 of about 48,191 (258)

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Signal Recognition Particle Myopathy With Cardiac Manifestations in Rheumatoid Arthritis

Annals of Internal Medicine: Clinical Cases
Immune-mediated necrotizing myopathy is a rare inflammatory myopathy characterized by progressive muscle weakness and potentially severe systemic complications.
Priya Sunkara, Deepesh Yadav, Murat Gokden, Vinisha Kota   +3 more
doaj   +1 more source

A 57‐Year‐Old Male With Behavioral Variant Frontotemporal Dementia and MATR3 and NOS3 Mutations

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This report presents a case of behavioral variant frontotemporal dementia caused by mutations in the MATR3 and NOS3 genes, aiming to analyze its clinical manifestations and genetic characteristics. For a case presenting with personality changes and gait abnormalities as the initial symptoms, this study conducted a comprehensive analysis of its
Feifei Lin, Saie Huang
wiley   +1 more source

From myositis to sarcoidosis: a rare autoimmune continuum

EULAR Rheumatology Open
: Background: Sarcoidosis is a multisystem granulomatous disease that may rarely coexist with idiopathic inflammatory myopathies. The overlap of sarcoidosis and idiopathic inflammatory myopathy is exceptional and poses diagnostic difficulties due to ...
Mert Can Ataca, Semih Gulle
doaj   +1 more source

A Case Report of Statin-Induced Immune-Mediated Necrotizing Myopathy Treatment Challenges

Case Reports in Rheumatology, 2022
Statin-induced necrotizing autoimmune myopathy is an immune-mediated necrotizing myopathy related to the use of statins. It is a very rare disease, which usually presents with proximal muscle weakness and frank elevation in creatine kinase levels ...
Anwar I. Joudeh, Mhd Kutaiba Albuni, Sara Seife Hassen, Phool Iqbal, Elsaid Mohamed Aziz Bedair, Salah Mahdi   +5 more
doaj   +1 more source

Analysis of clinical and histopathology characteristics of asymptomatic and pauci ⁃ symptomatic hyperCKemia

Chinese Journal of Contemporary Neurology and Neurosurgery, 2023
Objective To evaluate the diagnostic value of skeletal muscle biopsy in asymptomatic and pauci‑symptomatic hyperCKemia. Methods and Results A total of 146 patients with asymptomatic or pauci ‑ symptomatic hyperCKemia diagnosed in Peking University First ...
YUAN Yu‑jing, LIU Chang, XIE Zhi‑ying, ZHAO Ya‑wen, MENG Ling‑chao, LÜ He, WANG Zhao‑xia, YUAN Yun, ZHANG Wei   +8 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah, Sangmee S. Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

Inflammatory myopathy and severe rhabdomyolysis induced by leuprolide acetate therapy for prostate cancer: a case report

Journal of Medical Case Reports, 2011
Introduction Leuprolide acetate is a synthetic analog of gonadotropin-releasing hormone used for the treatment of prostate cancer. Its side effects are hot flashes, nausea, and fatigue.
Rohacek Martin, Bergner Michael, Erne Paul   +2 more
doaj   +1 more source

Whole-body MRI for full assessment and characterization of diffuse inflammatory myopathy [PDF]

Acta Radiologica Open, 2016
Background Conventional magnetic resonance imaging (MRI) is a highly valuable tool for full assessment of the extent of bilateral symmetrical diffuse inflammatory myopathy, owing to its high sensitivity in the detection of edema which correlates with ...
Saleh Saleh Elessawy, Eman Muhammad Abdelsalam, Eman Abdel Razek, Samar Tharwat   +3 more
doaj   +1 more source