Results 201 to 210 of about 1,221,115 (332)

SCORCH2: A Generalized Heterogeneous Consensus Model for High‐Enrichment Interaction‐Based Virtual Screening

open access: yesAdvanced Science, EarlyView.
Researchers developed SCORCH2, an advanced machine‐learning scoring function for virtual screening that combines two complementary XGBoost models to re‐evaluate protein‐ligand binding plausibility. The method demonstrates superior performance on standard benchmarks, shows excellent generalization to previously unseen protein targets, and provides ...
Lin Chen   +3 more
wiley   +1 more source

Artificial Intelligence Is Stereotypically Linked More with Socially Dominant Groups in Natural Language

open access: yesAdvanced Science, EarlyView.
AI is not seen through an unbiased lens. People tend to stereotype AI as competent and link it with socially advantaged groups—such as men, the wealthy, the young, and prestigious occupations—raising concerns that such perceptions may deepen existing social divides rather than bridge them.
Zixi Wang   +4 more
wiley   +1 more source

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

open access: yesAdvanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song   +17 more
wiley   +1 more source

Trends in medicare reimbursement for the resection of spinal tumors: 2000-2021. [PDF]

open access: yesNeurosurg Rev
Atluri S   +7 more
europepmc   +1 more source

Hyperspectral Fluorescence Imaging with a New Polarity‐Ultrasensitive Fluorescent Probe

open access: yesAdvanced Science, EarlyView.
Based on the critical role of the π‐spacer in determining wavelength sensitivity to microenvironmental polarity, a new fluorescent probe, Lipi‐PS is rationally developed, which exhibits the highest polarity‐sensitivity so far. Its integration with hyperspectral fluorescence imaging enables multiscale polarity mapping across cells, tissues, and ...
Ri Zhou   +7 more
wiley   +1 more source

From Knitting Technology to Robotics: Untethered Thermally Actuated Textile Exoskeleton for Dexterity Applications

open access: yesAdvanced Science, EarlyView.
A textile‐based exoskeleton glove with integrated thermally driven actuators achieves rapid, low‐power response for dexterous motion. Utilizing advanced knitting methods, embedded heaters, and hybrid yarn sensors, the glove bends in a segmented fashion under 12 s at only 10.8 W and 48 °C.
Ibrahim Adel Khamis Ahmed   +5 more
wiley   +1 more source

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