Results 171 to 180 of about 1,024,195 (297)

Programmable Nanobody‐Targeting Chimeras Enable Intracellular Viral Protein Degradation

Advanced Science, EarlyView.
Nab‐TAC enables targeted degradation of HBV surface antigen (HBsAg) in vivo. By fusing nanobody‐based recognition domains with programmable proteasome‐recruiting degradation signals, Nab‐TAC reduces HBsAg levels in a hydrodynamic HBV mouse model. ABSTRACT Chronic hepatitis B virus (HBV) infection remains a major global health challenge, largely because
Max Yu‐Chen Pan, Ting‐Hui Lee, Tzu‐Ning Peng, Eva Yi‐Hsuan Wu, Yu‐Ting Chiu, Chih‐Chien Chiu, Hong Vinh Nguyen, Yuan‐Shao Pao, Ming‐Hong Chao, Richard Kuan‐Lin Lee, Han‐Chung Wu, Lily Hui‐Ching Wang   +11 more
wiley   +1 more source

Monetary policy and inflation targeting in a small open-economy [PDF]

This paper investigates the transmission mechanism of monetary policy and inflation targeting in a small open-economy by using backward-looking of aggregate supply (AS) and aggregate demand (AD) framework.
Abdul Karim, Zulkefly, Md. Said, Fathin Faezah, Md. Thahir, Md. Zyadi, Jusoh, Mansor   +3 more
core  

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

Advanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong, Siang Chen, Maolin Li, Meng Wang, Hailin Zhang, Bolun Zhou, Zhenhua Xie, Chen Wang, Peng Gao, Jianjun Luo, Hanchun Yang, Runsheng Chen, Dongdong Zhang, Jie Li, Jun Han   +14 more
wiley   +1 more source

From policy presence to policy performance: implementation gaps in Philippine food and nutrition systems under systemic shocks. [PDF]

Public Health Nutr
Untalan KB, Pagote GJT, Tejero KRG.
europepmc   +1 more source

A Rigid–Foldable Kirigami‐Inspired Metamorphic Mechanism With Programmable Motion Modes and Self‐Locking

Advanced Science, EarlyView.
Geometric constraint reconfiguration enables a rigid–foldable kirigami‐inspired mechanism to switch between twisting, directional translation, and self‐locking states. By encoding multifunctionality directly into its architecture, the mechanism achieves multimodal motion and passive locking without reassembly, providing a compact platform for adaptive ...
Jianlin Wang, Zhongmin Song, Ketao Zhang
wiley   +1 more source

The Impact of Inflation Targeting on Unemployment in Developing and Emerging Economies [PDF]

Several countries around the world have adopted the inflation targeting regime for monetary policy. Despite the growing literature on the issue, it is not clear whether developing and emerging countries can improve their economic performance by adopting ...
Jose Angelo Divino
core  

Analysis of the Impact of Disaggregates Government Expenditure on Economic Growth in Iraq. [PDF]

F1000Res
Qasim Mohammed A, Khamis Abd M.
europepmc   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

"Inflation Targeting: A Critical Appraisal" [PDF]

Since the early 1990s, a number of countries have adopted Inflation Targeting (IT) in an effort to reduce inflation. Most literature has praised IT as a superior framework of monetary policy.
Malcolm Sawyer, Philip Arestis
core  

Insulin-Related Disordered Eating Behaviour: A Scoping Review of Evidence. [PDF]

Curr Diab Rep
Shelford A, Jenkins PE, Harvey K.
europepmc   +1 more source