Results 181 to 190 of about 140,820 (331)

When Biology Meets Medicine: A Perspective on Foundation Models

Advanced Intelligent Discovery, EarlyView.
Artificial intelligence, and foundation models in particular, are transforming life sciences and medicine. This perspective reviews biological and medical foundation models across scales, highlighting key challenges in data availability, model evaluation, and architectural design.
Kunying Niu, Yuxing Wang, Limin Zou, Jing Huang   +3 more
wiley   +1 more source

Lysine Oxidation by LOXL2 in Single Strands Versus Triple Helices: Implications for Collagen‐Related Diseases

Angewandte Chemie, EarlyView.
The oxidation of Lys residues in proline‐rich single‐stranded collagen by LOXL2, a key enzyme for tissue maturation and linked to diseases, was revealed. Oxidation occurs at rates comparable to or higher than those of Lys in unstructured telopeptides, the well‐known native sites of Lysyl oxidase (LOX) activity.
Laura M. Poller, Tomas Fiala, Helma Wennemers   +2 more
wiley   +2 more sources

Agreement among common core temperature indices in defining critical environmental limits for human thermoregulation: a secondary analysis. [PDF]

Am J Physiol Regul Integr Comp Physiol
Leach OK, Meade RD, van den Bogaard T, O'Connor FK, Daanen HAM, Kenney WL, Kenny GP.   +6 more
europepmc   +1 more source

SuperResNET: Model‐Free Single‐Molecule Network Analysis Software Achieves Molecular Resolution of Nup96

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
SuperResNET is a powerful integrated software that reconstructs network architecture and molecular distribution of subcellular structures from single molecule localization microscopy datasets. SuperResNET segments the nuclear pore complex and corners, extracts size, shape, and network features of all segmented nuclear pores and uses modularity analysis
Yahongyang Lydia Li, Ismail M. Khater, Christian Hallgrimson, Ben Cardoen, Timothy H. Wong, Ghassan Hamarneh, Ivan R. Nabi   +6 more
wiley   +1 more source

Regeneration‐Optimized Chemisorbents: Evaluating Hybrid Coordination Networks for Atmospheric Water Harvesting

Angewandte Chemie, EarlyView.
Atmospheric water harvesting (AWH) under arid conditions requires desiccants that load water below 30% RH and regenerate below 60°C, a performance regime traditionally limited to physisorbents. Here, we show that the inherent hydrolytic instability of M′FSIX‐25‐M coordination networks enable regeneration‐optimized chemisorbents (ROCs) with projected ...
Xiang‐Jing Kong, Asif Raza, Lilia Croitor, Andrey Bezrukov, Xia Li, Angela Shipman, William Morris, Carlos J. Solanilla‐Salinas, Adam Hogan, Brian Space, Volodymyr Bon, Stefan Kaskel, Soumya Mukherjee, Alan C. Eaby, Tao He, Michael J. Zaworotko   +15 more
wiley   +2 more sources

Mechanistic insights into the learning curve of cryoballoon ablation: ablation temperature mediates the effect of operator experience on radiation exposure. [PDF]

Front Cardiovasc Med
Li TY, Yu ZM.
europepmc   +1 more source

Crease‐Encoded Soft Origami Chambers: A Unified Design‐to‐Fabrication Framework for Low‐Pressure Pneumatic Joints

Advanced Intelligent Systems, EarlyView.
Origami turns a single silicone chamber into three different soft fluidic actuators. Crease angles alone decide whether it elongates, bends, or twists, and the fully folded chambers are cast monolithically in one day. Below 15 kPa, they reach 268% axial stretch, 72° bending, and 55° twist—no strain‐limiting layers, no rigid reinforcements, no vacuum ...
Alexia Le Gall, Mattia Franchi de’ Cavalieri, Gastone Ciuti, Arianna Menciassi, Matteo Cianchetti   +4 more
wiley   +1 more source

Integration of Liquid Handling Robotics, Turbidimetry, and Machine Learning Toward Inverse Design of Lower Critical Solution Temperature Polymer Formulations

Advanced Intelligent Systems, EarlyView.
An integrated OT‐2/plate reader platform automates LCST cloud point measurement of NIPAM‐co‐DMAEMA copolymers across high‐dimensional formulation spaces. Machine learning trained on the resulting high‐throughput datasets achieves R2 up to 0.96 and enables inverse design of polymer formulations to target transition temperatures with <1% error.
Lachlan Alexander, Vianna F. Jafari, Tanja Junkers   +2 more
wiley   +1 more source

Nonlinear association between stress hyperglycemia ratio and short-term and long-term mortality in sepsis patients with atrial fibrillation: a cohort study. [PDF]

Front Endocrinol (Lausanne)
Liang X, Li Y, Gui S.
europepmc   +1 more source

INVESTIGATING INFLECTION VIA LANGUAGE SIMULATION

, 2019
This thesis investigates the role of inflection in speech by modeling and simulating that aspect of language in computer simulation. This thesis proposes a simple language simulation model that can be used to tested the communicative power and methods of
Towne, Christopher
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