The Governance Gap: Democratizing Drug Development Through Decision Architecture
Drug development is most exposed to governance failure where it can least afford it, in global health. The field has more predictive power than at any point in its history and roughly the same failure rate it had a decade ago. We argue that this paradox persists because the field has invested heavily in prediction science while neglecting decision ...
Craig R. Rayner +16 more
wiley +1 more source
Development and external validation of the HCH and HPMS prognostic indices for sepsis: a retrospective model development study using a Multi-Objective Non-Newtonian Fluid optimization algorithm. [PDF]
Gao C +12 more
europepmc +1 more source
ABSTRACT This study investigates how internal governance design supports credible ESG performance by distinguishing between Incentive and Oversight Architectures. Using 13,993 firm‐year observations of US nonfinancial firms from 2018 to 2024, we estimate fixed effects and two‐step system GMM models.
Beyza Gürel +2 more
wiley +1 more source
Point-of-care ultrasound for emergency pericardiocentesis: a multidimensional CUSUM analysis of the learning curve. [PDF]
Tang X, Chen M, Chen Y, Zhong C, Yang X.
europepmc +1 more source
ABSTRACT This study examines how artificial intelligence language models influence corporate environmental, social, and governance greenwashing (GWESG$$ {\mathrm{GW}}_{\mathrm{ESG}} $$) behavior, utilizing panel data from Chinese listed firms spanning 2012–2022.
Brahim Bergougui +2 more
wiley +1 more source
A Shared Neural Mechanism for Abstract Grammatical Computations across Languages in Bilinguals. [PDF]
Chen XJ, Blanco-Elorrieta E.
europepmc +1 more source
ABSTRACT Scholars have documented that corporate social responsibility (CSR) is critical to firm performance, yet its impact on international expansion remains underexplored. CSR not only serves as a signaling mechanism in international markets but also entails substantial resource commitments.
Mingjie Fang +3 more
wiley +1 more source
Association between the lactate-to-albumin ratio and mortality in patients with protein-energy malnutrition: a retrospective cohort study. [PDF]
Xiao Z +9 more
europepmc +1 more source
ABSTRACT Corporations increasingly use Environmental, Social, and Governance (ESG) reports to articulate their commitments, priorities, and performance in sustainability governance. This study examines how Korean firms have configured and reconfigured their sustainability discourses across industries and time using 634 sustainability reports (2014–2024)
Taedong Lee +3 more
wiley +1 more source
Nutritional-inflammatory-metabolic indices associated with in-hospital mortality in acute kidney injury patients undergoing continuous renal replacement therapy: dose-response analysis and machine learning-based risk stratification. [PDF]
Cao Y +8 more
europepmc +1 more source

