Results 151 to 160 of about 104,746 (296)

A One-Dimensional (1D) Computational Fluid Dynamics Study of Fontan-Associated Liver Disease (FALD). [PDF]

open access: yesInt J Numer Method Biomed Eng
Li Y   +4 more
europepmc   +1 more source

CircTspan3 Promotes Cartilage Development Through ANNEXIN A2‐Mediated Ferroptosis and Apoptosis Inhibition and Exosome‐Mediated Paracrine Signaling

open access: yesAdvanced Science, EarlyView.
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan   +16 more
wiley   +1 more source

MDP25‐VDAC3 Complex Orchestrates Actin Remodeling and Mitochondrial Dynamics to Modulate Innate Immunity in Arabidopsis

open access: yesAdvanced Science, EarlyView.
This study reveals that actin remodeling regulates mitochondrial elongation as a defense strategy in plants. Flagellin perception induces fusion‐dependent elongation, supported by cortical actin bundles, to repair damage and boost ATP and ROS production.
Junxiu Hou   +5 more
wiley   +1 more source

Ring-like (Donut-Shaped) Intracranial Aneurysms: A Warning Morphology of Mural Jet Flow and Pre-Rupture Instability. [PDF]

open access: yesDiagnostics (Basel)
Nestorović D   +5 more
europepmc   +1 more source

Cancer Stem Cells Shift Metabolite Acetyl‐Coenzyme A to Abrogate the Differentiation of CD103+ T Cells

open access: yesAdvanced Science, EarlyView.
Lei et al. demonstrate that cancer stem cells (CSCs) play a pivotal role in impairing the differentiation of CD103+ T cells in patients with non‐small‐cell lung cancer. The key mechanism involves CSC‐derived acetyl‐CoA, which disrupts CD103+ T cell differentiation by sequentially inducing acetylation and ubiquitination of the Blimp‐1 protein. Targeting
Jiaxin Lei   +10 more
wiley   +1 more source

Foraminiferal isotopic evidence of abrupt mid-20th century onset of hydrographic instability in Nordic Seas inflow waters. [PDF]

open access: yesSci Rep
Sejrup HP   +6 more
europepmc   +1 more source

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