Results 211 to 220 of about 104,746 (296)

Spatial Heterogeneity and Methodological Insights in Fish Community Assessment: A Case Study in Hulun Lake. [PDF]

Biology (Basel)
Liu Z, Zhang Y, Pan Y, Ma Z, Han X, Zhou Z, Tian S, Sun B.   +7 more
europepmc   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Fetal Hepatic Circulation: From Vascular Physiology to Doppler Assessment. [PDF]

Diagnostics (Basel)
Gil-Santos I, Guedes-Martins L.
europepmc   +1 more source

Liver Stiffness Rises Early in MASLD and Drives Inflammation, Lipid Dysmetabolism, and Fibrosis via Piezo1–YAP Mechanotransduction

Advanced Science, EarlyView.
Progressive stiffening of the hepatic extracellular matrix and free fatty acid overload activate the mechanosensor Piezo1 in steatotic hepatocytes, inducing calcium influx and nuclear translocation of Yes‐associated protein. YAP‐dependent nuclear signaling further drives inflammatory and fibrotic gene programs, lipid metabolic reprogramming, and ...
Juan Ma, Ning Xie, Ziwei Wang, Xiru Liang, Yulong Han, Qiang Zhao, Ming Wang, Hongwei Lu, Wanyi Kou, William Alazawi, Jinhai Wang, Lu Li, Ning Liu, Na Liu, Haitao Shi, Feng Xu   +15 more
wiley   +1 more source

Impact of combined balance and strength exercise program on lower limb energy flow in individuals with knee osteoarthritis. [PDF]

Front Sports Act Living
Tangkanjanavelukul P, Khumtong N, Chaemklan K, Kumar Agrawal D, Rachnavy P.   +4 more
europepmc   +1 more source

Electric‐Fish‐Inspired Thin Hydrogel Electrocytes Achieve High Power Density and Environmental Robustness

Advanced Science, EarlyView.
This study presents thin, environmentally stable hydrogel power sources inspired by electric fish. Made using layer‐by‐layer spin‐coating with glycerol‐enhanced solutions, they offer precise layer control, long‐term hydration, and anti‐freezing stability.
Dor Tillinger, Wonbae Lee, Haley M. Tholen, Derek M. Hall, Joseph S. Najem   +4 more
wiley   +1 more source

Left atrial and ventricular impairment of asymptomatic pediatric myocarditis survivors: analysis by speckle tracking and exercise stress echocardiography. [PDF]

Quant Imaging Med Surg
Zhang L, Deng L, Zhang N, Ren X, Duan H, Hua Y, Wang C, Zhou K, Ma F, Shao S.   +9 more
europepmc   +1 more source

Resilient Calvarial Bone Marrow Supports Retinal Repair in Type 2 Diabetes

Advanced Science, EarlyView.
Skull bone (calvarium) marrow in diabetic mice stay structurally intact and keeps making blood cells, unlike the bone marrow of the leg bones. The skull marrow is exposed to cerebrospinal fluid (CSF), which contains protective molecules called oxysterols.
Bright Asare‐Bediako, Sergio Li Calzi, Julia G. Behnsen, Ram Prasad, Magdalena Blaszkiewicz, Yvonne Adu‐Rutledge, Robert F. Rosencrans, Jason L. Floyd, Ashley Rennhack, Denise Stanford, Anna Lin, Todd A. Lydic, Carl M. Sheridan, Michael E. Boulton, Kristy L. Townsend, Julia V. Busik, Maria B. Grant   +16 more
wiley   +1 more source

Assessment of physical parameters impacts on debris flow modeling with RAMMS. [PDF]

Sci Rep
Fan J, Galoie M.
europepmc   +1 more source

Traceless Regulation of Genetic Circuitry

Advanced Science, EarlyView.
Energy‐based, as opposed to molecular, control offers unprecedented improvements in key circuit parameters. This review summarizes the fundamentals of such traceless switches, categorizes them by trigger modalities, and compares and contrasts distinct advantages as well as shortcomings of each kind.
Gokberk Unal, Martin Fussenegger
wiley   +1 more source