Results 231 to 240 of about 104,746 (296)

Systematic review and meta-analysis of the role of aorto-hepatic conduits in liver transplant: Known knowns and known unknowns. [PDF]

open access: yesWorld J Transplant
Uragoda Appuhamilage B   +5 more
europepmc   +1 more source

ADAMTS9‐AS2 Disrupts Docetaxel‐Resistance in Castration‐Resistant Prostate Cancer via Stemness Suppression and Ferroptosis Induction

open access: yesAdvanced Science, EarlyView.
This study uncovered a dual‐track mechanism by which ADAMTS9‐AS2 overcame chemoresistance in CRPC: suppressing cancer stemness through the FOXF2/TGF‐β2 pathway, and triggering ferroptosis via competitive SLC7A11 sequestration. Polymeric materials co‐targeting these vulnerabilities further boost docetaxel sensitivity, highlighting a compelling strategy ...
Ji Liu   +12 more
wiley   +1 more source

A forensic engineering framework for flood management of cascade reservoir systems. [PDF]

open access: yesSci Rep
Zeinali M   +5 more
europepmc   +1 more source

Remote Activation of Spinal TRPV1 by Magnetic Nanocubes Confers Cardioprotection Against Myocardial Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
Fe‐based magnetic nanocubes conjugated with TRPV1 antibodies (FeNCs‐TRPV1) are developed for the specific targeting of TRPV1 channels. Intraspinally injected FeNCs‐TRPV1 induces TRPV1 desensitization in rats exposed to repetitive and transient ACMF.
Xueying Cheng   +15 more
wiley   +1 more source

Largest documented cerebral aneurysm mimicking a giant brain tumor and treated by highly selective occlusion of inflow: illustrative case. [PDF]

open access: yesJ Neurosurg Case Lessons
Andereggen L   +10 more
europepmc   +1 more source

Antibody‐Empowered Nanomedicine for Precise Biomedical Applications

open access: yesAdvanced Science, EarlyView.
This review explores strategies for functionalizing nanoparticles with antibodies to construct antibody‐empowered nanomedicine. It discusses the classification of these nanomedicines based on antibody structure, with a specific focus on their biomedical applications in diagnostics, bioimaging, and therapeutics for various diseases.
Chen Chen   +7 more
wiley   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

open access: yesAdvanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling   +17 more
wiley   +1 more source

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