Results 251 to 260 of about 445,748 (288)

Experimental investigation of the impact of gas generated via coal oxidation in the upstream coal goaf on the subsequent residual coal oxidation process. [PDF]

Sci Rep
Zhang B, Xing J.
europepmc   +1 more source

A Programmable, 3D Neuron‐On‐Chip Platform Integrating Near Real‐Time Biosensing and Multiaxial Loading for Mechanobiological Injury Profiling

Advanced Science, EarlyView.
A programmable 3D Neuron‐Injury‐on‐a‐Chip platform integrates multiaxial mechanical loading with ultrasensitive electrochemical biosensing to decode neuronal responses in real time. By mimicking physiologically relevant extension–torsion forces, the system reveals load‐specific biomarker trajectories (T‐Tau, NFL), gene regulation, and apoptosis.
Sultan Khetani, Kar Wey Yong, Mawafag F. Alhasadi, Amir Hamedzadeh, Leila Shahsavari, Atefeh Rafiei, Kalvin Wu, Omakhowa Agbojo, Anupriya Singh, Kunal Karan, Salvatore Federico, Arindom Sen, Amir Sanati‐Nezhad   +12 more
wiley   +1 more source

Structural valve deterioration is primarily caused by cyclic fatigue but not immune rejection. [PDF]

Front Immunol
Kostyunin AE, Glushkova TV, Ovcharenko EA, Onischenko PS, Klyshnikov KY, Akentieva TN, Bogdanov LA, Koshelev VA, Stasev AN, Khromov AA, Kutikhin AG.   +10 more
europepmc   +1 more source

Temporal Stretch‐Induced Nuclear Mechanosensing Coordinates Early Chromatin Accessibility and Genome Protection

Advanced Science, EarlyView.
Cyclic stretching of fibroblasts triggers coordinated nuclear mechanosensing events, including calcium ion release, perinuclear actin assembly, emerin translocation, and H3K9me3 loss, increasing chromatin accessibility for specific genes related to mechanotransduction and repair.
Hye‐Won Shim, Ji‐Young Yoon, Hwalim Lee, Shanika Karunasagara, Cheng Ji Li, Yongdae Shin, Sukbum Hong, Dong‐Joon Lee, Jung‐Hwan Lee, Kam W. Leong, Hae‐Won Kim   +10 more
wiley   +1 more source

Experimental characterization of complex atmospheric flows: A wind turbine wake case study. [PDF]

Sci Adv
Angelou N, Sjöholm M, Mikkelsen TK.
europepmc   +1 more source

Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections

Advanced Science, EarlyView.
This review highlights the dynamic plasticity of macrophages during pulmonary infections and proposes an integrative framework defining six functional subtypes: Inflam‐Ms, Hub‐Ms, Reg‐Ms, Prolif‐Ms, Memory‐Ms, and Senesc‐Ms. Single‐cell omics delineate their distinct roles in homeostasis and infection, refining our understanding of macrophage ...
Zhaoheng Lin, Yuxiao Zheng, Yu Zhong, Hongyan Wang   +3 more
wiley   +1 more source

Hemodynamic characteristics and drug deposition in cerebral aneurysm sac. [PDF]

Sci Rep
Singh D, Usmani AY, Upadhyay RK.
europepmc   +1 more source

Spatially Resolved Mapping of Voltage‐Gated Proton Channel Activity Reveals Delayed Proton Transport in Local Microenvironments

Advanced Science, EarlyView.
A revolutionary imaging platform integrating quantitative single‐molecule photobleaching with ratiometric fluorescence probes enables high‐throughput (≈2300 individually resolvable channels) mapping of individual proton channels in a large field (≈3000 µm2), overcoming the spatial and temporal limitations of conventional electrophysiology.
Jiahua Zhuang, Yang Xu, Yuxian Lu, Shiyang Lyu, Jie Tan, Jiandong Feng   +5 more
wiley   +1 more source

CT imaging of third inflow cases: a hidden cause of surgical complications and liver pseudolesions. [PDF]

BJR Case Rep
Cural Kula G, Durur Karakaya A.
europepmc   +1 more source

Piezo1 Upregulation in Monocyte‐Derived Macrophages Impairs Post‐Myocardial Infarction Cardiac Repair via Defective Efferocytosis and Enhanced Ferroptosis

Advanced Science, EarlyView.
This study reports early Piezo1 activation in bone marrow monocyte‐derived macrophages (MoMs) during myocardial infarction (MI), which governs the fate and function of recruited macrophages. The recruited MoMs with increased Piezo1 expression exhibit increased ferroptosis and defective efferocytosis, delayed clearance of dead cells and resolution of ...
Lu Peng, Yunlong Xia, Huishou Zhao, Yongzhen Guo, Xiaoming Xu, Xue Han, Shiyue Wang, Fengyue Ding, Quanchi Liu, Congye Li, Yuan He, Zhaoyi Luo, Qiaojuan Wang, Xing Zhang, Feng Gao, Yajing Wang, Yulin Li, Shengpeng Wang, Ling Tao, Wenjun Yan   +19 more
wiley   +1 more source