Results 81 to 90 of about 439,157 (305)

A Surface‐engineered Microfluidic Device for Antibody‐Mediated Negative Selection of High‐Quality Sperm for Assisted Reproduction

Advanced Functional Materials, EarlyView.
This study reports a microfluidic device with a functionalized surface utilizing a polyoxazoline coating and covalently immobilized gold nanoparticles and anti‐phosphatidylserine antibody. The device efficiently eliminates pre‐apoptotic and apoptotic spermatozoa and yields sperm with substantially improved quality and low DNA damage, offering a simple ...
Soraya Rasi Ghaemi, David J. Sharkey, Nicole O. McPherson, Markos Negash Alemie, Krasimir Vasilev, Sarah A. Robertson   +5 more
wiley   +1 more source

Unsteady Flow Characteristics in a 90 Degree Elbow Affected by Developed, Undeveloped and Swirling Inflow Conditions

Journal of Fluid Science and Technology, 2012
Laser Doppler Velocimetry (LDV) measurements in a 90 degree elbow of which the curvature radius coincides with its inner diameter were examined for the cases of inflow from a long pipe, short pipe and swirl generator.
Yukiharu IWAMOTO, Manabu KONDO, Hirotaka MINAMIURA, Masaaki TANAKA, Hidemasa YAMANO   +4 more
doaj   +1 more source

Estimation of mass outflow rates from dissipative accretion disc around rotating black holes

, 2017
We study the properties of the dissipative accretion flow around rotating black holes in presence of mass loss. We obtain the complete set of global inflow-outflow solutions in the steady state by solving the underlying conservation equations self ...
Aktar, Ramiz, Das, Santabrata, Nandi, Anuj, Sreehari, H.   +3 more
core   +1 more source

VIVID: A qPCR‐Based Platform for Sensitive and Quantitative In Vivo Tracking of Extracellular Vesicles

Advanced Functional Materials, EarlyView.
This study introduces VIVID (Vesicle In Vivo Identification using DNA), a qPCR‐based platform that tracks PCR‐amplifiable DNA tags loaded in the EVs for accurate and quantifiable EV biodistribution in vivo. ABSTRACT Extracellular vesicles (EVs) represent promising carriers for nucleic acid therapeutics, offering advantages over synthetic nanoparticles ...
Oscar Boyadjian, Talin Ebrahimian, Jonathan Miranda O'Connor, Janusz Rak, Stephanie Lehoux, Maryam Tabrizian   +5 more
wiley   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

The Impact of Inflow Angle on Aneurysm Hemodynamics: A Simulation Study Based on Patient-Specific Intracranial Aneurysm Models

Frontiers in Neurology, 2020
The inflow angle of intracranial aneurysms (IAs) can impact the hemodynamics of IAs, therefore it is likely to contribute to IA clinical rupture risk stratification.
Xiao Mo, Qianqian Meng, Xinjian Yang, Haiyun Li   +3 more
doaj   +1 more source

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

Advanced Functional Materials, EarlyView.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source

Searching for Inflow Towards Massive Starless Clump Candidates Identified in the Bolocam Galactic Plane Survey

, 2018
Recent Galactic plane surveys of dust continuum emission at long wavelengths have identified a population of dense, massive clumps with no evidence for on-going star formation. These massive starless clump candidates are excellent sites to search for the
Bosse, Carter, Bullivant, Christopher, Calahan, Jenny, Chance, Quadry, Choi, Sarah, Cook, Claire, Dunn, Marina, Gray, Laurin, Henrici, Andrew, Ivanov, Elizabeth, Jame-Frias, Ramon, Kearsley, Ian, Kelledy, Joseph, Lautenbach, Jennifier, Lewin, Collin, Mahmood, Qasim, McKinley, Scott, Mitchell, Adriana, Pascale, Massimo, Pulley, Anna, Robinson, Daniel, Schmid, Jonathan, Shirley, Yancy, Svoboda, Brian, Zawadzki, Nicole   +24 more
core   +1 more source

Tissue‐Stimulator Platform for Electrically Stimulating Pancreatic β‐Cells for Long‐Term Functional Regulation

Advanced Functional Materials, EarlyView.
We present a tissue‐stimulator platform for seamless electrode integration with pancreatic tissue, applying uniform electrical stimulation through optimized design with biohybrid 3D printing. Advantageous effects of electrical stimulation on β‐cell function were observed, including enhanced calcium signaling, islet morphology, and maturation.
Jihwan Kim, Uijung Yong, Myungji Kim, Jaewook Kim, Yeonggwon Jo, In Kyong Shim, Song Cheol Kim, Jinah Jang   +7 more
wiley   +1 more source

Effects of Continuous Rainfall and Runoff under Different Slope Conditions on Hillslope Soil Erosion in the Black Soil Region

Shuitu Baochi Xuebao
［Objective］ To investigate the characteristics of rill erosion on slopes under different slope gradients and rainfall-runoff conditions. ［Methods］ Continuous simulated rainfall and upper slope inflow tests were conducted to study the erosion processes on
WANG Tingting, SHEN Haiou, LIANG Yushi, LIU Jianxiang, ZHAO Qiang, WANG Xueying, TIAN Li   +6 more
doaj   +1 more source