Results 71 to 80 of about 139,233 (252)
Possibilistic Influence Diagrams
, 2008 . In this article we present the framework of Possibilistic Influence Diagrams (PID), which allow to model in a compact form problems of sequential decision making under uncertainty, when only ordinal data on transitions likelihood or preferences are ...
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
A Decision Analysis Approach to Electronics Standard Development Informed by Life Cycle Assessment Using Influence Diagrams. [PDF]
J Clean Prod, 2020 Garvey T +4 more
europepmc +1 more source
, 1995 Influence Diagrams (ids) are a graphic formalism able to provide a compact representation of decision problems. ids are based on the axioms of probability and decision theory, and they define a normative framework to model decision making. Unfortunately,
Marco Ramoni
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Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Our HERUS Jour Fixe seminars provide a dedicated platform for our team to exchange insights on research progress, ongoing projects, and other relevant topics.
Felix Martin Del Campo, Francisco Xavier
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The role of time in influence diagrams
, 2003 An influence diagram is a compact representation emphasizing the qualitative features of decision problem under uncertainty. Classical influence diagram has parameters stable in time, determined order of suggested decisions and generally is independent ...
Traczyk, W., Wiesław Traczy
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source