Results 111 to 120 of about 2,189,205 (291)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Health literacy level among university students in Xi'an City

open access: yes预防医学
Objective: To investigate the level of health literacy and its influencing factors among university students in Xi'an City, so as to provide the basis for improving the health literacy level among university students.
WU Yaqiong, FANG Xinzhu
doaj   +1 more source

Structure and features of Competitiveness Index [PDF]

open access: yes, 2013
Competitiveness is an important factor among social variables influencing youth’s health related behaviors, however the relationship between competitiveness and health behaviors is a less investigated field of research.
Fülöp, Márta   +4 more
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Prevalence of dyslipidemia and its influencing factors among adult residents in Hebei province: a cross-sectional survey

open access: yesZhongguo gonggong weisheng
ObjectiveTo investigate the prevalence of dyslipidemia and its influencing factors among adults in Hebei province, to provide a reference for the prevention and control of dyslipidemia in the population.
Qianyu LI   +8 more
doaj   +1 more source

Mapping factors influencing EAI adoption in the local government authorities on different phases of the adoption lifecycle [PDF]

open access: yes, 2008
Several private and public organisations have adopted Enterprise Application Integration (EAI), however, its application in the Local Government Authorities (LGAs) is limited.
Elliman, T, Kamal, M, Themistocleous, M
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Factors influencing thyroidectomy complications.

open access: yesBrazilian journal of otorhinolaryngology, 2012
The postoperative outcome of thyroidectomies is related to factors concerning the patient, the thyroid disease, and the surgeon.To analyze a clinic's experience with thyroidectomy complications.historical cross-sectional cohort study.We reviewed the charts from 228 patients submitted to thyroidectomy, between 1991 and 2004.
Neto, Miguel Ernandes   +6 more
openaire   +2 more sources

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

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