Results 211 to 220 of about 720,557 (266)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

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Analysis of the original influencing factors and secondary influencing factors of academic papers

Library Hi Tech, 2019
Purpose The influencing factors of academic papers have always been the focus of attention in the field of Scientometrics. Exploring the influencing factors of altmetrics indicators and traditional literature indicators on academic papers is beneficial to better explore the potential significance and value of academic papers in the evaluation of ...
Rongying Zhao
exaly   +2 more sources

Factors Influencing Learning and Factors Influencing Persistence

Proceedings of the 2017 International Conference on Information System and Data Mining, 2017
Massive open online courses have opened up access to courses from many highly-regarded universities to learners of diverse backgrounds, such as students, in-service staffs, and senior citizens. This study examined the specific factors that spurred different learners to learn, and the instructional design factors that motivated learners to persist.
Biyun Huang, Khe Foon Hew
openaire   +1 more source

Factors influencing prognosis

Gynecologic Oncology, 1974
Abstract An attempt is made to assess the usual pretreatment information thought to have prognostic significance in adenocarcinoma of the uterine corpus. Clinical impressions from reported series of treated patients plus results of follow-up on a small number of untreated patients were used.
J F, Nolan, P, Morrow, J, Anson
openaire   +2 more sources

Factors Influencing Hospital Resilience

Disaster Medicine and Public Health Preparedness, 2020
ABSTRACTThis study aims at investigating the influencing factors on hospital resilience. For this purpose, a systematic review of the literature was conducted. Six databases, including Web of Science, Scopus, SAGE, EBSCO, Google Scholar, and PubMed were searched for articles published between 2000 and 2018.
Afsaneh, Khademi Jolgehnejad, Reza, Ahmadi Kahnali, ALi, Heyrani   +2 more
openaire   +2 more sources

Factors that Influence Prescribing Decisions

Annals of Pharmacotherapy, 2004
BACKGROUND Strategies to control the quality and cost of medication use are largely dependent on the ability to alter selection of medications. Previous models of prescribing behavior have focused on physicians. In the hospital setting, clinical pharmacists and formulary committee members are also key players in
Glen T, Schumock, Surrey M, Walton, Hayley Y, Park, Edith A, Nutescu, Juan C, Blackburn, Jamie M, Finley, Richard K, Lewis   +6 more
openaire   +2 more sources

Ability factors and environmental influences.

American Psychologist, 1965
Walter VanDyke Bingham left with his will a memorandum suggesting that there be established, under the auspices of the American Psychological Association, an annual lectureship to call attention to the importance of the discovery and development of talented persons. His wishes have been carried out by Mrs.
openaire   +2 more sources

Factors Influencing Code-Switching

2014
This chapter discusses uniformity and variability in the choice of matrix language.
Parafita Couto, M. Del Carmen, Davies, Peredur, Carter, Diana, Deuchar, Margaret   +3 more
openaire   +2 more sources