Results 251 to 260 of about 20,459,832 (298)

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Identifying the influencing factors for cataract surgery uptake in Malaysia. [PDF]

PLoS One
Salowi MA, Naing NN, Tay JF, Wan Nawang WR, Sharudin SN, Mustafa N, Ngah NF.   +6 more
europepmc   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Research on the influencing factors of consumption behavior of agricultural organic waste derivatives. [PDF]

Sci Rep
Wei H, Yao J.
europepmc   +1 more source

Macroeconomic Factors do influencing Stock Price: A Case Study on Karachi Stock Exchange

, 2014
Muzammal Ilyas Sindhu
openalex   +1 more source

Factors Influencing Contraceptive Use among Women and Adolescents: A Study at Entebbe Grade B Hospital, Uganda [PDF]

Katushabe Della
openalex   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Analysis of spatial differentiation and influencing factors of rural industrial integration efficiency in China. [PDF]

PLoS One
Fang Y, Yang Y.
europepmc   +1 more source

Characterisation of the Full Pore Size Distribution of and Factors Influencing Deep Coal Reservoirs: A Case Study of the Benxi Formation in the Daning–Jixian Block at the Southeastern Margin of the Ordos Basin

Xiaoming Chen, Tao Wang, Song Wu, Ze Deng, J.P Li, Zhicheng Ren, Daojun Huang, Wentian Fan, Gengen Zhu   +8 more
openalex   +1 more source