Results 101 to 110 of about 476,517 (280)

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Complete genome sequencing of H1N1pdm09 swine influenza isolates from Nigeria reveals likely reverse zoonotic transmission at the human-animal interface in intensive piggery

open access: yesInfection Ecology & Epidemiology, 2019
Prevailing agro-ecological conditions and intermingling of human and animals in intensive farms in urban and peri-urban areas in Africa favour cross species transmission of pathogens at the human-animal interface.
C.A. Meseko   +3 more
doaj   +1 more source

The Situation for Influenza in the World in Summer 2015 and the Preliminary Forecast for the Upcoming Season 2015 - 2016

open access: yesЭпидемиология и вакцинопрофилактика, 2016
The analysis of the spatial-temporal distribution of influenza data weekly to WHO data in the summer of 2015 in the countries of the Southern and Northern hemispheres It is shown that in the Southern hemisphere registered a moderate influenza epidemics ...
O. L. Kiselev   +3 more
doaj   +1 more source

Epistatically interacting substitutions are enriched during adaptive protein evolution. [PDF]

open access: yesPLoS Genetics, 2014
Most experimental studies of epistasis in evolution have focused on adaptive changes-but adaptation accounts for only a portion of total evolutionary change. Are the patterns of epistasis during adaptation representative of evolution more broadly?
Lizhi Ian Gong, Jesse D Bloom
doaj   +1 more source

Nanomolecular detection of human influenza virus type A using reverse transcription loop-mediated isothermal amplification assisted with rod-shaped gold nanoparticles [PDF]

open access: yes, 2014
Reverse transcription loop-mediated isothermal amplification (RT-LAMP) and rod-shaped gold nanoparticles (gold nanorods; GNRs) were employed for nanomolecular detection of human influenza virus type A RNA.
Gill, P.   +3 more
core   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Vacinação contra o vírus influenza em gestantes: cobertura da vacinação e fatores associados

open access: yesEinstein (São Paulo)
OBJETIVO: Descrever a cobertura vacinal de gestantes para influenza e fatores associados à recusa ou à aceitação da vacina. MÉTODOS: Estudo descritivo, prospectivo, que incluiu 300 puérperas atendidas no Hospital e Maternidade Santa Joana (SP).
Renato de Ávila Kfouri   +1 more
doaj   +1 more source

Avian influenza virus and human: pandemic concern and threat? [PDF]

open access: yesReviews in Clinical Medicine, 2016
Type A influenza viruses causes infections in human and animals, especially in birds. Wild aquatic birds are the natural hosts for all known influenza type A viruses. Avian type viruses are divided into two groups: highly pathogenic avian influenza (HPAI)
Mohammad Derakhshan
doaj   +1 more source

Intranodal administration of mRNA encoding nucleoprotein provides cross-strain immunity against influenza in mice [PDF]

open access: yes, 2019
Background: Current human influenza vaccines lack the adaptability to match the mutational rate of the virus and therefore require annual revisions. Because of extensive manufacturing times and the possibility that antigenic alterations occur during ...
Aerts, Joeri   +8 more
core   +2 more sources

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

open access: yesFEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal   +2 more
wiley   +1 more source

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