Results 151 to 160 of about 325,943 (270)

Advanced Materials for Biological Field‐Effect Transistors (Bio‐FETs) in Precision Healthcare and Biosensing

Advanced Healthcare Materials, EarlyView.
This review explores how advanced materials enhance Bio‐FETs for precision healthcare and biosensing. It covers their working principles, surface functionalization, and ultra‐sensitive detection capabilities. The integration of flexible designs, AI, and IoT for real‐time monitoring is discussed, along with challenges like material reproducibility and ...
Minal Pandey, Manish Bhaiyya, Prakash Rewatkar, Jitendra B. Zalke, Nitin P. Narkhede, Hossam Haick   +5 more
wiley   +1 more source

Influenza and influenza like illness in human populations in Uganda [PDF]

International Journal of Infectious Diseases, 2012
W. Mangeni, Hannah Kibuuka, Denis K. Byarugaba, L. Luswa, B. Erima, M. Milland, Derrick Mimbe, Edison Mworozi, Josephine Bwogi   +8 more
openaire   +2 more sources

Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response

Advanced Healthcare Materials, EarlyView.
In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim, Jin Woong Lee, Piper A. Rawding, Mari Iida, Carter Kim, Kourtney L. Kostecki, Michael J. Poellmann, Bridget Crossman, Ashley S. Liu, YoungSoo Kim, Deric L. Wheeler, Seungpyo Hong   +11 more
wiley   +1 more source

Multifunctional Neural Probes Enable Bidirectional Electrical, Optical, and Chemical Recording and Stimulation In Vivo

Advanced Materials, EarlyView.
Convergence drawing is used to create flexible, microscale, multifunctional fiber‐based neural probes. Optimized materials selection enables individual devices to perform neural recording, electrical stimulation, optogenetics, fiber photometry, fluid delivery, and voltammetric neurotransmitter detection in rodents.
Nicolette Driscoll, Marc‐Joseph Antonini, Taylor M. Cannon, Pema Maretich, Greatness Olaitan, Valerie Doan Phi Van, Keisuke Nagao, Atharva Sahasrabudhe, Emmanuel Vargas Paniagua, Ethan J. Frey, Ye Ji Kim, Sydney Hunt, Melissa Hummel, Sanju Mupparaju, Alan Jasanoff, B. Jill Venton, Polina Anikeeva   +16 more
wiley   +1 more source

Protein‐Like Polymers Targeting Keap1/Nrf2 as Therapeutics for Myocardial Infarction

Advanced Materials, EarlyView.
We describe a Keap1 targeting protein‐like polymer (PLP) which activates Nrf2, an important cytoprotective transcription factor for relieving myocardial infarction‐induced oxidative stress. This PLP increases cell survival in vitro in multiple relevant cardiac cell types and elicits pro‐reparative responses, improving cardiac function in a preclinical ...
Joshua M. Mesfin, Kendal P. Carrow, Alexander Chen, Madeline P. Hopps, JoJo J. Holm, Quincy P. Lyons, Michael B. Nguyen, Jervaughn D. Hunter, Assa Magassa, Elyse G. Wong, Kate Reimold, Sriya N. Paleti, Emily Gardner, Matthew P. Thompson, Colin G. Luo, Xiaoyu Zhang, Karen L. Christman, Nathan C. Gianneschi   +17 more
wiley   +1 more source

Formulation and Characterization of Novel Ionizable and Cationic Lipid Nanoparticles for the Delivery of Splice‐Switching Oligonucleotides

Advanced Materials, EarlyView.
Lipid nanoparticles (LNPs) of unconventional composition and defined structures are investigated as small oligonucleotide carriers. A composition is identified that outperforms Onpattro in cargo delivery to HeLa cells. The structure of these LNPs resembles a micellar cubic phase not commonly associated with high‐performing LNPs.
Miina Ojansivu, Hanna M. G. Barriga, Margaret N. Holme, Stefanie Morf, James J. Doutch, Samir EL Andaloussi, Tomas Kjellman, Markus Johnsson, Justas Barauskas, Molly M. Stevens   +9 more
wiley   +1 more source

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

Advanced Materials, EarlyView.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding, Bing Liu, Andreas Peil, Sisi Fan, Jie Chao, Na Liu   +5 more
wiley   +1 more source

Electrospinning and Nanofiber Technology: Fundamentals, Innovations, and Applications

Advanced Materials, EarlyView.
This review explores electrospinning fundamentals, methods for synthesizing polymer, metal oxide, carbon, and composite nanofibers, and advancements in fiber architectures like porous, core–shell, and aligned structures. It highlights applications in functional membranes, sensors, energy systems, and catalyst design while addressing future ...
Yujang Cho, Jong Won Beak, Mingyu Sagong, Seongcheol Ahn, Jong Seok Nam, Il‐Doo Kim   +5 more
wiley   +1 more source

Using QCM‐D for Real‐Time Analysis of Cell Adhesion Dynamics at Biointerfaces

Advanced Materials Interfaces, EarlyView.
This study explores adhesion of human fibroblasts to functionalized biomaterial surfaces. Quartz crystal microbalance with dissipation (QCM‐D) is used to measure cell responses in real time. The QCM‐D signalis correlated with changes in cell morphology and focal adhesion kinase (FAK) activation. This data shows a positive correlation between the energy
Agnes Rogala, Hanna Tiainen, Daria Zaytseva‐Zotova   +2 more
wiley   +1 more source

Targets of influenza human T-cell response are mostly conserved in H5N1. [PDF]

mBio
Sidney J, Kim A-R, de Vries RD, Peters B, Meade PS, Krammer F, Grifoni A, Sette A.   +7 more
europepmc   +1 more source