Results 251 to 260 of about 476,517 (280)

The Nuclear Localization of ACLY Guards Early Embryo Development Through Recruiting P300 and HAT1 to Promote Histone Acetylation and Transcription

Advanced Science, EarlyView.
ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma, Yingyi Zhang, Weijie Yang, Xiaomei Tong, Siya Liu, Yan Zhou, Mengjia Qiu, Huifang Jiang, Zhanhong Hu, Peipei Ren, Yan Rong, Mengru Lai, Jiamin Jin, Fei Huang, Liujian Ouyang, Feng Zhou, Heng‐Yu Fan, Yin‐Li Zhang, Songying Zhang   +18 more
wiley   +1 more source

Exploring the respiratory viral landscape beyond influenza and SARS-CoV-2: a 2020-2023 study in Fujian, China. [PDF]

Front Public Health
You L, Zhang Z, Li H, Weng Y.
europepmc   +1 more source

Listerin Alleviates Alzheimer's Disease through IRE1‐mediated Decay of TLR4 mRNA

Advanced Science, EarlyView.
Alzheimer's disease (AD) progression is influenced by microglia‐mediated neuroinflammation. Here, it is demonstrated that Listerin suppresses neuroinflammatory signaling and cognitive impairment in AD models by triggering IRE1α‐mediated TLR4 mRNA decay. Adenoviral Listerin delivery reduces amyloid‐β pathology, positioning it as a new therapeutic target.
Fei Qin, Runyu Cao, Xuemei Bai, Jiahua Yuan, Wanwei Sun, Yi Zheng, Xiaopeng Qi, Wei Zhao, Bingyu Liu, Chengjiang Gao   +9 more
wiley   +1 more source

Dynamic Interaction Between SARS-CoV-2 and Influenza A Virus Infection in Human Respiratory Tissues and Cells. [PDF]

Microorganisms
Ho JCW, Ng K, Ching RHH, Peiris M, Nicholls JM, Chan MCW, Hui KPY.   +6 more
europepmc   +1 more source

Clade 2.3.4.4b highly pathogenic H5N1 influenza viruses from birds in China replicate effectively in bovine cells and pose potential public health risk. [PDF]

Emerg Microbes Infect
Xiong J, Ding S, Zhou J, Cui Y, Chen X, Huang L, Zhang J, Qi W, Liao M.   +8 more
europepmc   +1 more source

Responding to avian influenza in poultry farms in Victoria, Australia. [PDF]

Bull World Health Organ
Blaney K, Cardamone L, Clarke NE, Hayes MJ, Muleme M, McNamara BJ, Jalil E, Holwill S, Lim CK, O'Brien H, Layton E, Fidao A, Salmon S, Kinnear R, Ford M, Hussain MA, Athan E.   +16 more
europepmc   +1 more source

Assessment of the public health risk of novel reassortant H3N3 avian influenza viruses that emerged in chickens. [PDF]

mBio
Li H, Tong Q, Tao M, Li J, Yu H, Han Q, Wu J, Lan R, Han J, Chang H, Li Y, Pu J, Sun Y, Liu L, Qu Y, Li Q, Lu L, Liu J, Sun H.   +18 more
europepmc   +1 more source

The Seroprevalence of Influenza A Virus Infections in Polish Cats During a Feline H5N1 Influenza Outbreak in 2023. [PDF]

Viruses
Golke A, Dzieciątkowski T, Szaluś-Jordanow O, Czopowicz M, Witkowski L, Żychska M, Domańska E, Jańczak D, Nalbert T, Lesceu S, Paszkowska M, Giergielewicz J, Frymus T.   +12 more
europepmc   +1 more source