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Characterization of emerging H3N3 avian influenza viruses in poultry in China. [PDF]

Emerg Microbes Infect
Yan C, Shi J, Cui P, Chen Y, Wang C, Wang Y, Miao J, Zhang Y, Kong H, Zeng X, Tian G, Li C, Suzuki Y, Deng G, Chen H.   +14 more
europepmc   +1 more source

Influenza coinfection inhibits control of mycobacterial infection in a human challenge model

Broderick C, Powell O, Nichols S, D'Souza G, Habgood-Coote D, Miranda-Sole C, Whettlock E, Gardener Z, Bergstrom E, Wright V, Woods C, Chiu C, Newton S, Whittaker L, Levin# M, Kaforou M.   +15 more
europepmc   +1 more source

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Avian influenza and human health

Acta Tropica, 2002
Natural infections with influenza A viruses have been reported in a variety of animal species including humans, pigs, horses, sea mammals, mustelids and birds. Occasionally devastating pandemics occur in humans. Although viruses of relatively few HA and NA subtype combinations have been isolated from mammalian species, all 15 HA subtypes and all 9 NA ...
Dennis J. Alexander, Ilaria Capua
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A “universal” human influenza A vaccine

Virus Research, 2004
We have previously reported on a universal human influenza A vaccine, based on the external domain of the transmembrane viral M2-protein (M2e) [Nature Medicine 5 (1999) 1119]. M2-protein is scarcely present on the virus but is abundantly expressed on virus-infected cells.
Walter Fiers, M De Filette, Sabine Neirynck, Ashley J. Birkett, W. Min Jou   +4 more
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The pathogenesis of influenza in humans

Reviews in Medical Virology, 2001
AbstractThe rapid evolution of influenza A and B viruses contributes to annual influenza epidemics in humans. In addition, pandemics of influenza are also caused by influenza A viruses, whereas influenza B does not have the potential to cause pandemics because there is no animal reservoir of the virus. Study of the genetic differences between influenza
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Predicting the Evolution of Human Influenza A

Science, 1999
Eighteen codons in the HA1 domain of the hemagglutinin genes of human influenza A subtype H3 appear to be under positive selection to change the amino acid they encode. Retrospective tests show that viral lineages undergoing the greatest number of mutations in the positively selected codons were the progenitors of future H3 lineages in 9 of 11 recent ...
Robin M. Bush, Catherine A. Bender, Walter M. Fitch, Kanta Subbarao, Nancy J. Cox   +4 more
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Animal and human influenzas

Revue Scientifique et Technique de l'OIE, 2014
Influenza type A viruses affect humans and other animals and cause significant morbidity, mortality and economic impact. Influenza A viruses are well adapted to cross species barriers and evade host immunity. Viruses that cause no clinical signs in wild aquatic birds may adapt in domestic poultry to become highly pathogenic avian influenza viruses ...
Malik Peiris, Hui-Ling Yen
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Human infection with influenza H9N2

The Lancet, 1999
Summary We report the clinical features of two cases of human infection with influenza A virus subtype H9N2 in Hong Kong, and show that serum samples from blood donors in Hong Kong had neutralising antibody suggestive of prior infection with influenza H9N2.
Leung, CW, Yuen, KY, Peiris, M, Shortridge, KF, Orr, WK, Lai, RWM, Ip, PLS, Chan, KH   +7 more
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Avian Flu to Human Influenza

Annual Review of Medicine, 2006
Influenza A viral infection causes substantial annual morbidity and mortality worldwide, particularly for infants, the elderly, and the immunocompromised. The virus mainly replicates in the respiratory tract and is spread by respiratory secretions. A growing concern is the recent identification of H5N1 strains of avian influenza A in Asia that were ...
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‘Ravages of Influenza’: The Human Cost of Influenza in Ireland

2021
This chapter examines two distinct aspects of the pandemic in Ireland, how and where did influenza enter Ireland? What was the human cost to the country? It explores theories about the origin of this global pandemic and considers how and where influenza entered Ireland as well as theories on factors contributing to the dispersal of the disease ...
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