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The Lancet, 2017
Influenza is an acute respiratory illness, caused by influenza A, B, and C viruses, that occurs in local outbreaks or seasonal epidemics. Clinical illness follows a short incubation period and presentation ranges from asymptomatic to fulminant, depending on the characteristics of both the virus and the individual host.
Catharine I. Paules, K. Subbarao
semanticscholar +6 more sources
Influenza is an acute respiratory illness, caused by influenza A, B, and C viruses, that occurs in local outbreaks or seasonal epidemics. Clinical illness follows a short incubation period and presentation ranges from asymptomatic to fulminant, depending on the characteristics of both the virus and the individual host.
Catharine I. Paules, K. Subbarao
semanticscholar +6 more sources
A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes
Science, 2022Seasonal influenza vaccines offer little protection against pandemic influenza virus strains. It is difficult to create effective prepandemic vaccines because it is uncertain which influenza virus subtype will cause the next pandemic.
C. P. Arevalo +17 more
semanticscholar +1 more source
Der Internist, 2021
Influenza is the infectious disease with the highest population-based mortality. It mainly affects those aged 60 years and older, mainly due to immune senescence, which also favors complicated courses and compromises vaccine effectiveness. Therefore, various approaches have been developed for more immunogenic vaccines, which are now available for use ...
Anja, Kwetkat +3 more
openaire +2 more sources
Influenza is the infectious disease with the highest population-based mortality. It mainly affects those aged 60 years and older, mainly due to immune senescence, which also favors complicated courses and compromises vaccine effectiveness. Therefore, various approaches have been developed for more immunogenic vaccines, which are now available for use ...
Anja, Kwetkat +3 more
openaire +2 more sources
Expert Opinion on Pharmacotherapy, 2000
The currently available antiviral drugs rimantadine and amantadine are effective only for influenza A viruses. Another class of influenza antiviral drugs is the neuraminidase inhibitors, which selectively inhibit both influenza A and B viruses. Recent studies have found the neuraminidase inhibitors zanamivir and oseltamivir to be 67-82% effective in ...
M D, Khare, M, Sharland
+7 more sources
The currently available antiviral drugs rimantadine and amantadine are effective only for influenza A viruses. Another class of influenza antiviral drugs is the neuraminidase inhibitors, which selectively inhibit both influenza A and B viruses. Recent studies have found the neuraminidase inhibitors zanamivir and oseltamivir to be 67-82% effective in ...
M D, Khare, M, Sharland
+7 more sources
Host and viral determinants of influenza A virus species specificity
Nature Reviews Microbiology, 2018 Jason S Long +2 more
exaly +2 more sources
The human antibody response to influenza A virus infection and vaccination
Nature Reviews Immunology, 2019 Florian H Krammer
exaly +2 more sources
A brief review of influenza virus infection
Journal of Medical Virology, 2021Influenza is an acute viral respiratory infection that affects all age groups and is associated with high mortality during pandemics, epidemics, and sporadic outbreaks.
Mostafa Javanian +5 more
semanticscholar +1 more source
Infectious Disease Clinics of North America, 1998
Influenza viruses are unique in their ability to cause recurrent epidemics and truly global pandemics during which acute febrile respiratory disease occurs explosively in all age groups. Epidemics of varying severity occur almost annually in temperate climates and are punctuated by the much less frequent but more dramatic occurrence of pandemic ...
Cox, N. J., Fukuda, K.
openaire +4 more sources
Influenza viruses are unique in their ability to cause recurrent epidemics and truly global pandemics during which acute febrile respiratory disease occurs explosively in all age groups. Epidemics of varying severity occur almost annually in temperate climates and are punctuated by the much less frequent but more dramatic occurrence of pandemic ...
Cox, N. J., Fukuda, K.
openaire +4 more sources
The evolution of seasonal influenza viruses
Nature Reviews Microbiology, 2017 Velislava N Petrova, Colin A Russell
exaly +2 more sources
DMW - Deutsche Medizinische Wochenschrift, 2013
Yearly epidemics and occasional pandemics with Influenza have been observed for several hundred years. During the last pandemic the reported deaths due to confirmed influenza was lower than expected. New epidemiologic analyses demonstrate that the severity has probably been underestimated. In addition, cohort data from severely ill patients support the
B, Salzberger, W, Jilg
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Yearly epidemics and occasional pandemics with Influenza have been observed for several hundred years. During the last pandemic the reported deaths due to confirmed influenza was lower than expected. New epidemiologic analyses demonstrate that the severity has probably been underestimated. In addition, cohort data from severely ill patients support the
B, Salzberger, W, Jilg
openaire +4 more sources