Results 131 to 140 of about 132,310,386 (202)
Advanced Healthcare Materials, EarlyView.Open‐port, barrier‐free microfluidic device for modeling early metastatic progression. A centrally positioned tumor spheroid releases invasive cells that migrate through the surrounding matrix and intravasate into endothelialized lateral channels.
Vira Sharko +7 more
wiley +1 more source
Bioprinted Stiffness‑Tunable Pancreatic Microniches to Decode Early Tumor Initiation Mechanisms
Advanced Healthcare Materials, EarlyView.Stiffness‐tunable GelMA microniches generated by microvalve bioprinting preserve wild‐type acinar identity while revealing a nonlinear, Kras‐dependent response to matrix mechanics. Intermediate stiffness promotes acinar‐to‐ductal metaplasia and proliferation, defining a permissive mechanical window.
Aurelien Mazet +11 more
wiley +1 more source
Manual for the laboratory diagnosis and virological surveillance of influenza [PDF]
T his manual was jointly developed by five World Health Organization Collaborating Centres (WHOCCs) for influenza (the WHOCC for Reference and Research on Influenza, Melbourne, Australia; the WHOCC for Reference and Research on Influenza, Tokyo, Japan ...
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Advanced Healthcare Materials, EarlyView.ART@PLGA@GH‐A microspheres are developed via microfluidic technology for intra‐articular delivery of artemisinin. The system remodels rheumatoid arthritis microenvironments by regulating metabolic and inflammatory disorders, reducing lactate‐driven histone lactylation and cellular senescence, while restoring cartilage homeostasis and protecting joint ...
Shijie Meng +10 more
wiley +1 more source
Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization
Advanced Materials, EarlyView.A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab +8 more
wiley +1 more source
Advanced Materials, EarlyView.A chemically defined PEG‐based microgel platform enables scalable, reproducible production of three‐dimensional microgel‐iPSC constructs in multiple sizes. The system is compatible with high‐throughput automation and supports human iPSC expansion and differentiation within a single construct, including directed differentiation into cardiac organoids ...
Laura Klasen +8 more
wiley +1 more source
Estimating infection attack rates and severity in real-time during an influenza pandemic
, 2011 The 4th ESWI Influenza Conference, Saint-Julian's, Malta, 11-14 September ...
Hung, IFN +14 more
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Advanced Materials, EarlyView.In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren +6 more
wiley +1 more source
A Noninvasive Approach to Study Localized Forces in 3D Epithelia
Advanced Materials, EarlyView.Epithelial morphogenesis depends on dynamic mechanical coupling between adhesion complexes and the cytoskeleton, yet its regulation in polarized 3D tissues remains elusive. We developed a noninvasive strategy using cell‐like elastic microbeads to quantify local forces in intact epithelia.
Niels Gouirand +9 more
wiley +1 more source