Cross-neutralizing antibodies to pandemic 2009 H1N1 and recent seasonal H1N1 influenza A strains influenced by a mutation in hemagglutinin subunit 2. [PDF]
PLoS Pathogens, 2011 Pandemic 2009 H1N1 influenza A virus (2009 H1N1) differs from H1N1 strains that circulated in the past 50 years, but resembles the A/New Jersey/1976 H1N1 strain used in the 1976 swine influenza vaccine. We investigated whether sera from persons immunized
Wei Wang +9 more
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Assessment of pre and postinfection immunity to the hemagglutinin proteins of Influenza A(H1N1)pdm09 and Influenza A(H3N2) in India: a retrospective longitudinal study [PDF]
Virology JournalBackground Hemagglutinin (HA), one of the main surface glycoproteins of the influenza virus, is essential for viral entry into host cells. Antibodies targeting HA can neutralize the virus, offering protection against infection.
Anup Jayaram +10 more
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Mayo Clinic Proceedings, 2010 Within 2 months of its discovery last spring, a novel influenza A (H1N1) virus, currently referred to as 2009 H1N1, caused the first influenza pandemic in decades. The virus has caused disproportionate disease among young people with early reports of virulence similar to that of seasonal influenza.
Seth J, Sullivan +3 more
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Incidence and epidemiology of hospitalized influenza cases in rural Thailand during the influenza A (H1N1)pdm09 pandemic, 2009-2010. [PDF]
PLoS ONE, 2012 BACKGROUND: Data on the burden of the 2009 influenza pandemic in Asia are limited. Influenza A(H1N1)pdm09 was first reported in Thailand in May 2009.
Henry C Baggett +14 more
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Pandemic (H1N1) 2009 influenza [PDF]
New South Wales Public Health Bulletin, 2010 On 11 June 2009, the World Health Organization declared the first human influenza pandemic since 1968–1969. The responsible virus, pandemic (H1N1) 2009 influenza, is a novel triple-reassortant influenza A virus, incorporating avian, swine and human influenza genes.1 The virus is resistant to the anti-influenza medications, amantadine and rimantadine ...
Ben, Polkinghorne +2 more
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Complex patterns of human antisera reactivity to novel 2009 H1N1 and historical H1N1 influenza strains. [PDF]
PLoS ONE, 2012 During the 2009 influenza pandemic, individuals over the age of 60 had the lowest incidence of infection with approximately 25% of these people having pre-existing, cross-reactive antibodies to novel 2009 H1N1 influenza isolates.
Donald M Carter +6 more
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Journal of Infection in Developing Countries, 2011 Introduction: The Swine Origin A H1N1 Influenza Virus (SOIV) pandemic emerged in April 2009 affecting people and health-care systems worldwide. This study examined the differences among the early clinical features presented in confirmed SOIV cases ...
Monica Rodríguez-Valero +6 more
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Novel pandemic influenza A(H1N1) viruses are potently inhibited by DAS181, a sialidase fusion protein. [PDF]
PLoS ONE, 2009 The recent emergence of a novel pandemic influenza A(H1N1) strain in humans exemplifies the rapid and unpredictable nature of influenza virus evolution and the need for effective therapeutics and vaccines to control such outbreaks. However, resistance to
Gallen B Triana-Baltzer +14 more
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Emerging Infectious Diseases, 2016 In 2015, a novel influenza A(H1N1) virus was isolated from a boy in China who had severe pneumonia. The virus was a genetic reassortant of Eurasian avian-like influenza A(H1N1) (EA-H1N1) virus.
Wenfei Zhu +19 more
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Characterization of the 2009 pandemic A/Beijing/501/2009 H1N1 influenza strain in human airway epithelial cells and ferrets. [PDF]
PLoS ONE, 2012 BACKGROUND: A novel 2009 swine-origin influenza A H1N1 virus (S-OIV H1N1) has been transmitted among humans worldwide. However, the pathogenesis of this virus in human airway epithelial cells and mammals is not well understood.
Penghui Yang +14 more
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