Results 181 to 190 of about 114,186,541 (190)

The new pandemic influenza A/(H1N1)pdm09 virus: is it really “new”?

Journal of preventive medicine and hygiene, 2016
In June 2009 the World Health Organization (WHO)  issued a pandemic alert concerning the spread of an influenza A (H1N1) virus showing distinctive genetic characteristics vis-à -vis both seasonal influenza strains and vaccine strains. The most relevant mutation occurred in the hemagglutinin (HA).
BALDO, VINCENZO, BERTONCELLO, CHIARA, COCCHIO, SILVIA, FONZO, MARCO, PILLON, PIERANGELO, BUJA, ALESSANDRA, BALDOVIN, TATJANA   +6 more
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Adaptive evolution of PB1 from influenza A(H1N1)pdm09 virus towards an enhanced fitness

Virology, 2023
PB1 influenza virus retain traces of interspecies transmission and adaptation. Previous phylogenetic analyses highlighted mutations L298I, R386K and I517V in PB1 to have putatively ameliorated the A(H1N1)pdm09 adaptation to the human host. This study aimed to evaluate the reversal of these mutations and infer the role of these residues in the virus ...
Luís A. Santos, Filipe Almeida, Marta Gíria, João Trigueiro-Louro, Helena Rebelo-de-Andrade   +4 more
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Sequence-based identification and characterization of nosocomial influenza A(H1N1)pdm09 virus infections

Journal of Hospital Infection, 2012
Highly transmissible viruses such as influenza are a potential source of nosocomial infections and thereby cause increased patient morbidity and mortality.To assess whether influenza virus sequence data can be used to link nosocomial influenza transmission between individuals.Dutch A(H1N1)pdm09-positive specimens from one hospital (N = 107) were ...
Jonges, M, Rahamat-Langendoen, JC, Meijer, A, Niesters, HG, Koopmans, M   +4 more
openaire   +5 more sources

Clinical findings in 10 children with H275Y influenza A(H1N1)pdm09 virus infection

Pediatrics International, 2015
AbstractBackgroundLittle is known about the clinical effectiveness of neuraminidase inhibitors against H275Y influenza A(H1N1)pdm09 virus. A cluster of H275Y influenza A(H1N1)pdm09 virus with cross‐resistance to oseltamivir and peramivir was detected among untreated community patients in Hokkaido, Japan, during the 2013–2014 influenza season ...
Fujio, Kakuya, Takahiro, Kinebuchi, Hiroaki, Fujiyasu, Ryosuke, Tanaka, Hitoshi, Okubo, Hiroki, Kano   +5 more
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Natural A(H1N1)pdm09 influenza virus infection case in a pet ferret in Taiwan.

The Japanese journal of veterinary research, 2014
Ferrets have demonstrated high susceptibility to the influenza virus. This study discusses a natural 2009 pandemic influenza A (H1N1) (A(H1N1)pdm09) virus infection in a pet ferret (Mustela putorius furo) identified in Taiwan in 2013. The ferret was in close contact with family members who had recently experienced an influenza-like illness (ILI).
Lin, Hui-Ting, Wang, Ching-Ho, Wu, Wen-Ling, Chi, Chau-Hwa, Wang, Lih Chiann   +4 more
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Hemagglutinin variants of influenza A(H1N1)pdm09 virus with reduced affinity for sialic acid receptors

Archives of Virology, 2013
In influenza A H1 virus, amino acids at position 190 and 225 of HA affect replication and transmission. In this study, we show that the mutation D190Y in the HA of influenza AH1N1pdm09 virus reduces the affinity of the virus for sialic acid receptors expressed at the surface of red blood cells from different species without affecting virus replication ...
G, Ayora-Talavera, L, Cetina-Montejo, A, Matos-Patrón, L, Romero-Beltrán   +3 more
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[Emerged Pdm09 influenza virus increased purifying selection of seasonal H1N1 influenza virus].

Bing du xue bao = Chinese journal of virology, 2013
Pdm09 virus outbreak occurred in Mainland China in May 2009, a few months later, the prevalence of seasonal H1N1(sH1N1) influenza virus that already circulated in human for tens of years began to decline and disappeared afterwards. To identify the reason for the rapid decline of sH1N1 in mainland China, we sequenced the HA1 of sH1N1 during 2006-2011 ...
Yu, Lan, Wei-Juan, Huang, Hong-Tao, Sui, Xi-Yan, Li, Xiang, Zhao, Ming, Li, Yao-Yao, Chen, Jun-Feng, Guo, Yan-Hui, Cheng, Min-Ju, Tan, Zhao, Wang, Ning, Xiao, He-Jiang, Wei, Da-Yan, Wang, Yue-Long, Shu   +14 more
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Antiviral treatment and vaccination for influenza A(H1N1)pdm09 virus: lessons learned from the pandemic

Enfermedades Infecciosas y Microbiología Clínica, 2012
The influenza pandemic that was declared by the World Health Organization in June 2009 created a new scenario for the use of influenza antivirals and vaccination. The new strain, influenza A(H1N1)pdm09, was resistant to amantadine and rimantadine, and the most frequently used antiviral was oseltamivir.
Francisco, López-Medrano, María Carmen, Fariñas, Antonio, Payeras, Jerónimo, Pachón   +3 more
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Influenza A(H1N1)pdm09 Virus: Therapeutics and Challenges

Future Virology, 2012
Shailendra K Saxena, Rosaiah Kotikalapudi, Sneham Tiwari, Charuvaka Muvva   +3 more
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Activity of Thermopsis schischkinii Alkaloids Against Influenza A(H1N1)pdm09 Virus

Chemistry of Natural Compounds, 2015
I. P. Tsypysheva, E. G. Galkin, I. P. Baikova, N. I. Fedorov, P. R. Petrova, Ya. R. Orshanskaya, V. A. Fedorova, V. V. Zarubaev   +7 more
openaire   +1 more source