Results 91 to 100 of about 2,843,834 (270)

Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao   +15 more
wiley   +1 more source

Chicken cyclophilin A is an inhibitory factor to influenza virus replication

open access: yesVirology Journal, 2010
Background The importance of enhancing influenza resistance in domestic flocks is quite clear both scientifically and economically. Chicken is very susceptible to influenza virus.
Sun Lei   +4 more
doaj   +1 more source

Nanotherapy for Neural Retinal Regeneration

open access: yesAdvanced Science, EarlyView.
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu   +11 more
wiley   +1 more source

Origins and evolutionary genomics of the novel 2013 avian-origin H7N9 influenza A virus in China: Early findings [PDF]

open access: yesarXiv, 2013
In March and early April 2013, a new avian-origin influenza A (H7N9) virus (A-OIV) emerged in the eastern China. During the first week of April, the 18 infection cases have been confirmed and 6 people have died since March. This virus has caused global concern as a potential pandemic threat.
arxiv  

RESULTS OF IMMUNIZATION BY MEANS OF ACTIVE VIRUS OF HUMAN INFLUENZA 1 [PDF]

open access: bronze, 1937
Joseph Stokes   +4 more
openalex   +1 more source

Immunity Debt for Seasonal Influenza After the COVID‐19 Pandemic and as a Result of Nonpharmaceutical Interventions: An Ecological Analysis and Cohort Study

open access: yesAdvanced Science, EarlyView.
This study provides support for the immunity debt hypothesis, revealing a 131.72% increase in influenza rates during winter and a 161.23% rise in summer, 1 year following the global easing of COVID‐19 restrictions. This study offers empirical evidence of immunity debt on a global level, highlighting the importance of incorporating this concept into the
Li Chen   +6 more
wiley   +1 more source

A stochastic model for the evolution of the influenza virus [PDF]

open access: yesarXiv, 2013
Consider a birth and death chain to model the number of types of a given virus. Each type gives birth to a new type at rate $\lambda$ and dies at rate 1. Each type is also assigned a fitness. When a death occurs either the least fit type dies (with probability $1-r$) or we kill a type at random (with probability $r$).
arxiv  

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