Results 91 to 100 of about 945,008 (390)
Advanced Functional Materials, EarlyView.A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria +7 more
wiley +1 more source
Results of Epidemiological Monitoring Bird Flu in Kyrgyz Republic
Эпидемиология и вакцинопрофилактика, 2016 The results of the study with modern molecular genetic research methods the circulation in the Kyrgyzstan territory avian flu virus in waterfowl and humans.
K. T. Kasymbekova +3 more
doaj +1 more source
Monomeric Nucleoprotein of Influenza A Virus
PLoS Pathogens, 2013 Isolated influenza A virus nucleoprotein exists in an equilibrium between monomers and trimers. Samples containing only monomers or only trimers can be stabilized by respectively low and high salt. The trimers bind RNA with high affinity but remain trimmers, whereas the monomers polymerise onto RNA forming nucleoprotein-RNA complexes.
Chenavas, Sylvie +8 more
openaire +9 more sources
Advanced Functional Materials, EarlyView.A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao +11 more
wiley +1 more source
BMC Infectious Diseases, 2019 Background Influenza is a global infectious disease with a large burden of illness and high healthcare costs. Those who experience greater burden of disease include younger and older people, and pregnant women.
Kam Cheong Wong +2 more
doaj +1 more source
Virology Journal, 2023 Background Influenza A viruses have undergone rapid evolution with virulent; however, complete and comprehensive data on gene evolution and amino acid variation of HA and NA in immunosuppressed patients was few.
Yafen Liu +8 more
doaj +1 more source
, 2008 AIM: To determine the effectiveness of serial influenza vaccination. SCOPE: Studied in a Scottish GP population, the overall seroresponse rate increased with annual influenza vaccinations and after 5 years it increased from 45.1% to 93.3% for influenza ...
Carman, WF +4 more
core +1 more source
Advanced Functional Materials, EarlyView.Two kinds of self‐assembled RNA micelles were used to co‐deliver synergistic siRNA and nucleoside analogues for the treatment of colorectal cancer lung metastases. Near‐complete elimination of lung cancer metastases was confirmed in an orthotopic lung metastasis model constructed using human colorectal cancer lung metastases patient surgical samples to
Kai Jin +4 more
wiley +1 more source
US healthcare costs attributable to type A and type B influenza
Human Vaccines & Immunotherapeutics, 2017 While the overall healthcare burden of seasonal influenza in the United States (US) has been well characterized, the proportion of influenza burden attributable to type A and type B illness warrants further elucidation.
Songkai Yan +2 more
doaj +1 more source
Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents
Advanced Functional Materials, EarlyView.Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras +6 more
wiley +1 more source