Results 171 to 180 of about 2,843,834 (270)

Autocrine GDF10 Inhibits Hepatic Stellate Cell Activation via BMPR2/ALK3 Receptor to Prevent Liver Fibrosis

Advanced Science, EarlyView.
Liver fibrosis is a growing global health burden with no specific treatment. HSC activation is the predominant driver of liver fibrogenesis and the current focus in antifibrotic drug discovery. This study identifies autocrine GDF10 activates BMPR2/ALK3‐SMAD1/5/8‐SMAD7 pathway to counteract the TGF‐β‐SMAD2/3 pathway in HSCs, thereby inhibiting HSC ...
Yinliang Zhang, Xiaochen Gai, Yuhui Li, Zuoyu Chen, Xi Zhang, Wei Qiao, Ping Qiu, Chunyuan Du, Sufang Sheng, Jingran Hao, Yujie Zhang, Heng Fan, Xiaorong Li, Ming Liu, Jun Zhang, Zhe Pan, Yongsheng Chang   +16 more
wiley   +1 more source

Genomic Surveillance and Evolutionary Dynamics of Influenza A Virus in Sri Lanka  [PDF]

Virol J
Jayadas T, Jeewandara C, Senadheera B, Kuruppu H, Wickramanayaje R, Bary F, Wijewickrama A, Manilgama S, Gamage M, Perera N, Ogg G, MALAVIGE G.   +11 more
europepmc   +3 more sources

Risk Assessment of Spread of the Influenza A Virus in Cows in South Bulgaria. [PDF]

Viruses
Goujgoulova G, Koev K.
europepmc   +1 more source

Influenza Viruses of Type B Isolated in Nagasaki and Saga Prefectures

, 1953
Katsumitsu JOYA, Kaoru HAYASHI, Shigehisa ORI, Shigezumi YOSHIMURA   +3 more
openalex   +2 more sources

FABP4 as a Mediator of Lipid Metabolism and Pregnant Uterine Dysfunction in Obesity

Advanced Science, EarlyView.
Obesity during late pregnancy contributes to uterine smooth muscle dysfunction, but the underlying mechanisms are unclear. This study identifies fatty acid binding protein 4 (FABP4) as a key player in the process, mediating excessive fatty acid uptake, lipid accumulation, and mitochondrial dysfunction in myometrial cells. FABP4 could be a novel uterine
Xuan Li, Huihui Yu, Ruixian Tian, Xingxing Wang, Ting Xing, Chenyi Xu, Tengteng Li, Xue Du, Qianqian Cui, Biao Yu, Yunxia Cao, Zongzhi Yin   +11 more
wiley   +1 more source

STUDIES ON THE MECHANISM OF ADAPTATION OF INFLUENZA VIRUS TO MICE [PDF]

, 1947
George K. Hirst
openalex   +1 more source

IFITM2 Modulates Endocytosis Maintaining Neural Stem Cells in Developing Neocortex

Advanced Science, EarlyView.
This study reveals IFITM2 as a key regulator of endocytosis in radial glial cells (RGCs) during brain development. IFITM2's YXXø motif and phosphoinositide‐binding residues (K82/K87) are essential for endosome formation. IFITM2 deficiency disrupts the embryonic cortical neurogenesis, revealing a conserved mechanism linking endocytic dynamics to neural ...
Yuqing Lv, Wenzheng Zou, Lin Li, Shukui Zhang, Jiaqi Liang, Jiali Pu, Jianwei Jiao   +6 more
wiley   +1 more source

Genomics of novel influenza A virus (H18N12) in bats, Caribe Colombia. [PDF]

Sci Rep
Echeverri-De la Hoz D, Martínez-Bravo C, Gastelbondo-Pastrana B, Rivero R, López Y, Bertel V, Alemán-Santos M, Garay E, Hoyos R, Arrieta G, Ramírez JD, Mattar S.   +11 more
europepmc   +1 more source

THE INFECTION OF MICE WITH SWINE INFLUENZA VIRUS [PDF]

, 1935
Richard E. Shope
openalex   +1 more source

C1q+ Macrophage–Tumor Cell Interaction Promoted Tumorigenesis via GPR17/PI3K/AKT Pathway Induced DNA Hypermethylation in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
In the TME of NPC, C1q secreted by C1q+ TAMs interacted with GPR17 to activate PI3K/AKT signaling through strengthening GPR17 coupling PI3K and increasing calcium levels in tumor cells. The activated PI3K/AKT signaling further induces DNA hypermethylation to promote the malignancy and stemness of tumor cells.
Yunzhi Liu, Cuicui Huang, Min Luo, Wenfu Lu, Baifeng Zhang, Lu Bai, Shuyue Zheng, Yanan Tan, Shanshan Li, Huali Wang, Lanqi Gong, Xinyuan Guan   +11 more
wiley   +1 more source