Results 291 to 300 of about 928,120 (339)

Human influenza A H5N1 virus related to a highly pathogenic avian influenza virus

The Lancet, 1998
In May, 1997, a 3-year-old boy in Hong Kong was admitted to the hospital and subsequently died from influenza pneumonia, acute respiratory distress syndrome, Reye's syndrome, multiorgan failure, and disseminated intravascular coagulation. An influenza A H5N1 virus was isolated from a tracheal aspirate of the boy.
Claas, ECJ, Osterhaus, Ab, Beek, Ruud, Jong, Jan, Rimmelzwaan, Guus, Senne, DA, Krauss, S, Shortridge, KF, Webster, RG   +8 more
openaire   +4 more sources

Biology of Influenza A Virus

Annals of the New York Academy of Sciences, 2007
Abstract:  The outbreaks of avian influenza A virus in poultry and humans over the last decade posed a pandemic threat to human. Here, we discuss the basic classification and the structure of influenza A virus. The viral genome contains eight RNA viral segments and the functions of viral proteins encoded by this genome are described.
Cheung, TKW, Poon, LLM
openaire   +4 more sources

A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes

Science, 2022
Seasonal influenza vaccines offer little protection against pandemic influenza virus strains. It is difficult to create effective prepandemic vaccines because it is uncertain which influenza virus subtype will cause the next pandemic.
C. P. Arevalo, M. Bolton, Valerie Le Sage, Naiqing Ye, Colleen Furey, Hiromi Muramatsu, M. Alameh, N. Pardi, E. Drapeau, Kaela Parkhouse, Tyler A. Garretson, J. S. Morris, L. Moncla, Ying K. Tam, Steven H. Y. Fan, S. Lakdawala, D. Weissman, S. Hensley   +17 more
semanticscholar   +1 more source

Influenza A Virus Reassortment

2014
Reassortment is the process by which influenza viruses swap gene segments. This genetic exchange is possible due to the segmented nature of the viral genome and occurs when two differing influenza viruses co-infect a cell. The viral diversity generated through reassortment is vast and plays an important role in the evolution of influenza viruses ...
John, Steel, Anice C, Lowen
openaire   +2 more sources

Influenza A Virus: Cellular Entry

2023
The frequent emergence of pathogenic viruses with pandemic potential has posed a significant threat to human health and economy, despite enormous advances in our understanding of infection mechanisms and devising countermeasures through developing various prophylactic and therapeutic strategies. The recent coronavirus disease (COVID-19) pandemic has re-
Yasuyuki, Miyake, Yuya, Hara, Miki, Umeda, Indranil, Banerjee   +3 more
openaire   +2 more sources

A brief review of influenza virus infection

Journal of Medical Virology, 2021
Influenza is an acute viral respiratory infection that affects all age groups and is associated with high mortality during pandemics, epidemics, and sporadic outbreaks.
Mostafa Javanian, Mohammad Barary, S. Ghebrehewet, Veerendra Koppolu, VeneelaKrishna Rekha Vasigala, S. Ebrahimpour   +5 more
semanticscholar   +1 more source

Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus Infection in Domestic Dairy Cattle and Cats, United States, 2024

Emerging Infectious Diseases
We report highly pathogenic avian influenza A(H5N1) virus in dairy cattle and cats in Kansas and Texas, United States, which reflects the continued spread of clade 2.3.4.4b viruses that entered the country in late 2021.
Eric R. Burrough, Drew R. Magstadt, B. Petersen, Simon J. Timmermans, P. Gauger, Jianqiang Zhang, Chris Siepker, Marta Mainenti, Ganwu Li, Alexis C. Thompson, Patrick J. Gorden, Paul J. Plummer, R. Main   +12 more
semanticscholar   +1 more source

Influenza A Virus Neuraminidase Inhibitors

2022
Depending on the strain, influenza A virus causes animal, zoonotic, pandemic, or seasonal influenza with varying degrees of severity. Two surface glycoprotein spikes, hemagglutinin (HA) and neuraminidase (NA), are the most important influenza A virus antigens.
Nongluk, Sriwilaijaroen, Christopher J, Vavricka, Hiromasa, Kiyota, Yasuo, Suzuki   +3 more
openaire   +2 more sources

Influenza virus serology—a comparative study

Journal of Virological Methods, 1999
Virus isolation or influenza virus antigen detection are the most rapid tests for diagnosis in the acute stage of influenza virus infection. As serology is easier to carry out, the synthesis of serum IgM, IgA and IgG was studied in two well-defined patient groups, infected with influenza B virus (cohort 1, n = 37) and influenza A virus (cohort 2, n ...
Rothbarth, PH (Philip), Groen, J, Bohnen, Arthur, Garhasbi, M, Osterhaus, Ab   +4 more
openaire   +2 more sources