Results 91 to 100 of about 620,463 (308)

Influenza Virus in Human Exhaled Breath: An Observational Study [PDF]

, 2010
Background: Recent studies suggest that humans exhale fine particles during tidal breathing but little is known of their composition, particularly during infection.
Chan, Kwok Hung, Cowling, Benjamin J., DeHaan, Wesley H., Fabian, Patricia, Fouchier, Ron A. M., Fung, Rita O. P., Leung, Gabriel M., McDevitt, James J, Milton, Donald Kirby   +8 more
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

IL-17A Promotes Pulmonary B-1a Cell Differentiation via Induction of Blimp-1 Expression during Influenza Virus Infection [PDF]

, 2016
B-1 cells play a critical role in early protection during influenza infections by producing natural IgM antibodies. However, the underlying mechanisms involved in regulating this process are largely unknown.
Chen, M, Ko, KH, Lu, L, Ma, K, Wang, H, Zheng, B   +5 more
core   +2 more sources

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Epidemiology and ARIMA model of positive-rate of influenza viruses among children in Wuhan, China: A nine-year retrospective study

International Journal of Infectious Diseases, 2018
Objective: Influenza is a common childhood disease and protecting children by predicting the positive rate of influenza virus is important as vaccines are not routinely administered in China.
Zhirui He, Hongbing Tao
doaj   +1 more source

Defective interfering virus protects elderly mice from influenza [PDF]

, 2011
Background: We have identified and characterised a defective-interfering (DI) influenza A virus particles containing a highly deleted segment 1 RNA that has broad-spectrum antiviral activity.
Scott, P. D. (Paul D.), Meng, Bo, Marriott, Anthony C., Easton, A. J. (Andrew J.), Dimmock, N. J.   +4 more
core   +3 more sources

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Patterns of influenza B circulation in Latin America and the Caribbean, 2010-2017.

PLoS ONE, 2019
ObjectiveThere are limited published data about the circulation of influenza B/Victoria and B/Yamagata in Latin America and the Caribbean (LAC) and most countries have a vaccine policy that includes the use of the trivalent influenza vaccine. We analyzed
Rakhee Palekar, Angel Rodriguez, Cinthia Avila, Gisela Barrera, Miriam Barrera, Hebleen Brenes, Alfedo Bruno, Nathalie El Omeiri, Rodrigo Fasce, Walquiria Ferreira de Almeida, Danilo Franco, Maribel Huaringa, Jenny Lara, Roxana Loayza, Irma Lopez-Martinez, Terezinha Maria de Paiva, Jose Medina, Jenny Ojeda, Alba Maria Ropero, Viviana Sotomayor, Cynthia Vazquez, Marta Von Horoch   +21 more
doaj   +1 more source

Protective efficacy against pandemic influenza of seasonal influenza vaccination in children in Hong Kong: a randomized controlled trial [PDF]

, 2012
BACKGROUND: The efficacy of seasonal influenza vaccination against 2009 pandemic influenza A(H1N1) remains unclear. METHODS: One child aged 6-17 years in each of 796 households was randomized to receive 2009-2010 seasonal trivalent inactivated influenza ...
Chan, KH, Cheng, CKY, Chiu, SS, Cowling, BJ, Fang, VJ, Ip, DKM, Leung, GM, Ma, ESK, Ng, S, Peiris, JSM, So, HC, Wai, W, Wong, JY   +12 more
core   +1 more source