Results 81 to 90 of about 620,463 (308)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Clinical similarities between influenza A and B in children: a single-center study, 2017/18 season, Korea

open access: yesBMC Pediatrics, 2019
Background The global burden of seasonal influenza on medical care has been one of the greatest in the pediatric population. The attention drawn to influenza B was relatively low compared to influenza A, probably because the influenza B virus was thought
Yu Na Oh   +5 more
doaj   +1 more source

Patterns of influenza B circulation in Brazil and its relevance to seasonal vaccine composition

open access: yesBrazilian Journal of Infectious Diseases, 2016
Data on the burden of disease and circulation patterns of influenza B lineages for Brazil are limited. This review aims to describe the pattern of influenza B occurrence in Brazil to have a better understanding of its epidemiology and its relevance when ...
Eliana Nogueira Castro de Barros   +4 more
doaj   +1 more source

Clinical characteristics and outcomes of influenza A and B virus infection in adult Australian hospitalised patients

open access: yesBMC Infectious Diseases, 2020
Background Influenza B is often perceived as a less severe strain of influenza. The epidemiology and clinical outcomes of influenza B have been less thoroughly investigated in hospitalised patients.
Yogesh Sharma   +3 more
doaj   +1 more source

Human Cytomegalovirus Inhibitor AL18 Also Possesses Activity against Influenza A and B Viruses [PDF]

open access: yes, 2012
AL18, an inhibitor of human cytomegalovirus DNA polymerase, was serendipitously found to also block the interaction between the PB1 and PA polymerase subunits of influenza A virus.
Cruciani, Gabriele   +6 more
core   +2 more sources

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

The epidemiological signature of influenza B virus and its B/Victoria and B/Yamagata lineages in the 21st century.

open access: yesPLoS ONE, 2019
We describe the epidemiological characteristics, pattern of circulation, and geographical distribution of influenza B viruses and its lineages using data from the Global Influenza B Study.
Saverio Caini   +54 more
doaj   +1 more source

Haemophilus influenzae Type B Septicaemia [PDF]

open access: yesBMJ, 1969
In the period November 1967 to September 1968 Haemophilus influenzae type b was isolated from the blood of 11 young children. Only three of these presented with meningitis; others had septic arthritis, oesteomyelitis, subcutaneous abscesses, cellulitis, respiratory infections, and undifferentiated pyrexia. During the preceding five years H.
openaire   +2 more sources

Occurrence of influenza among patients hospitalized for suspicion of influenza A (H1N1) infection in 2010 at a sentinel hospital in São Paulo, Brazil [PDF]

open access: yes, 2011
In 2010, 96 patients suspected of being infected with the influenza A (H1N1) virus were hospitalized at the Hospital São Paulo, located in the city of São Paulo, Brazil.
Bellei, Nancy Cristina Junqueira   +5 more
core   +2 more sources

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

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