Results 141 to 150 of about 243,088 (257)

Influenza A virus hemagglutinin (HA); influenza B HA [PDF]

Science-Business eXchange, 2012
openaire   +1 more source

Ascites circRNA ASCOR Drives Platinum Resistance of High‐Grade Serous Ovarian Cancer by Facilitating RPA1 Nuclear Translocation

Advanced Science, EarlyView.
High‐grade serous ovarian carcinoma (HGSOC) is plagued by platinum resistance, with malignant ascites closely linked to poor outcomes. Here, we identify ASCOR, a circRNA enriched in ascites small extracellular vesicles (sEVs) from platinum‐resistant HGSOC patients, as a predictor of poor survival. ASCOR enhances platinum resistance in vitro and in vivo
Hanyuan Liu, Chenchen Zhu, Xuelin Yao, Yi Liu, Jing Zhu, Yuebo Li, Hanjie Xu, Cheng Peng, Ge Shan, Liang Chen, Ying Zhou   +10 more
wiley   +1 more source

N-glycosylation at the receptor binding site drives differences in receptor binding specificity between influenza B virus lineages. [PDF]

J Virol
Page CK, Mubassir MHM, Chopra P, Gay LC, Geiger G, Ray SD, Shepard JD, Miller RJ, Perez D, Bahl J, Boons GJ, Tompkins SM.   +11 more
europepmc   +1 more source

Existing Evidence for Influenza B Virus Adaptations to Drive Replication in Humans as the Primary Host. [PDF]

Viruses, 2023
Pekarek MJ, Weaver EA.
europepmc   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Sulfatide Binds to Influenza B Virus and Enhances Viral Replication. [PDF]

Viruses
Kurebayashi Y, Wakabayashi Y, Takahashi T, Sakakibara K, Takahashi S, Minami A, Suzuki T, Takeuchi H.   +7 more
europepmc   +1 more source

Targeting PRKCN, an Essential Driver Orchestrating mTOR‐IRF4 Axis Independently of Kinase Activity, in Multiple Myeloma

Advanced Science, EarlyView.
Constitutive PRKCN expression is driven by super‐enhancers and modulated by NF‐κB signaling in multiple myeloma (MM). PRKCN activates mTORC1/2‐IRF4 signaling axis and favors tumor cell growth independently of its kinase activity. IRF4 reciprocally promotes PRKCN transcription, creating a feed‐forward loop.
Koukou Tang, Dongpeng Jiang, Peng Ke, Xiaosen Bian, Lili Zhang, Ying Zhang, Tingting Zhu, Weiwei Qu, Wenhui Qi, Yang Xu, Chengcheng Fu, Depei Wu, Jianhong Chu   +12 more
wiley   +1 more source

One-Step RAA and CRISPR-Cas13a Method for Detecting Influenza B Virus. [PDF]

Microb Biotechnol
Zhang X, Chen S, Li J, Liu DA, Lai J, Song X, Hu R, Qiu Y, Chen K, Xu Y, Li X.   +10 more
europepmc   +1 more source

Microfluidic‐Driven Lipid Nanoparticles for Improved miRNA Delivery via Endo‐Lysosomal Trafficking Optimization

Advanced Science, EarlyView.
This study investigates the impact of various post‐processing methods (filtration, sonication, dialysis, and heating) on lipid nanoparticles produced using microfluidics. The nanoparticles are designed for efficient delivery of miRNA into cells. The work highlights how processing conditions influence nanoparticle stability and quality, providing ...
Alicja Kosik‐Kozioł, Michał Pruchniewski, Daniel Rybak, Piotr Jenczyk, Karolina Zakrzewska, Magdalena Bartolewska, Sławomir Błoński, Paweł Nakielski, Filippo Pierini   +8 more
wiley   +1 more source

Characterisation of an influenza B virus-derived peptide presented by HLA-B*18:01. [PDF]

Biochem J
Murdolo LD, Liwei Leong S, Maddumage JC, Mifsud NA, Chatzileontiadou DSM, Grant EJ, Gras S.   +6 more
europepmc   +1 more source