Results 11 to 20 of about 14,686,195 (254)

Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase [PDF]

, 2010
This work was supported by the Medical Research Council and the Scottish Funding Council.Influenza virus sialidase has an essential role in the virus’ life cycle.
Russell, Rupert James Martin, Thomson, Robin J, Thomson, Robin, Dyason, Jeffrey C, von Itzstein, M, Naffakh, Nadia, S. Kerry, Philip, Nadia Naffakh, Mark von Itzstein, Faith J. Rose, Rameix-Welti, Marie-Anne, Robin J. Thomson, Dyason, Jeffrey, Dyason, JC, Rupert J. M. Russell, van der Werf, S, Russell, Rupert J M, Santosh Rudrawar, Rose, Faith J, Russell, Rupert JM, Kerry, Philip Stephen, Jeffrey C. Dyason, von Itzstein, Mark, Thomson, RJ, J.M. Russell, Rupert, Rudrawar, S, Marie-Anne Rameix-Welti, Kerry, Philip S, Rose, FJ, Naffakh, N, Rameix-Welti, MA, Philip S. Kerry, van Der Werf, Sylvie, Rose, Faith, Rudrawar, Santosh, Sylvie van der Werf   +35 more
core   +2 more sources

New thiopyrano[2,3-d][1,3]thiazole derivatives as potential antiviral agents [PDF]

The Ukrainian Biochemical Journal, 2016
A series of novel thiopyrano[2,3-d][1,3]thiazole derivatives were synthesized and evaluated for their antiviral activity in vitro within AACF NIAID programme.
N. I. Zelisko, I. L. Demchuk, R. B. Lesyk   +2 more
doaj   +1 more source

Cloned defective interfering influenza virus protects ferrets from pandemic 2009 influenza A virus and allows protective immunity to be established [PDF]

, 2012
Influenza A viruses are a major cause of morbidity and mortality in the human population, causing epidemics in the winter, and occasional worldwide pandemics.
Cheung, Linda, Dimmock Nigel J., Dove, Brian K., Scott, P. D. (Paul D.), Carroll, Miles W., Linda Cheung, Miles W Carroll, Brian K Dove, Dove Brian K., Taylor Irene, Bassam Hallis, Meng, Bo, Easton, A. J. (Andrew J.), Marriott, Anthony C., Hallis, Bassam, Miles W. Carroll (111071), Dimmock, N. J., Linda Cheung (71020), Andrew J. Easton (111072), Irene Taylor (111066), Scott Paul D., Bo Meng (111065), Hallis Bassam, Taylor, Irene, Andrew J Easton, Paul D Scott, Bo Meng, Brian K. Dove (111063), Meng Bo, Paul D. Scott (111064), Nigel J Dimmock, Marriott Anthony C., Irene Taylor, Anthony C Marriott, Nigel J. Dimmock (111061), Carroll Miles W., Cheung Linda, Bassam Hallis (111069), Easton Andrew J., Anthony C. Marriott (111070)   +39 more
core   +2 more sources

Complexes of Oligoribonucleotides with D-Mannitol Inhibit Hemagglutinin–Glycan Interaction and Suppress Influenza A Virus H1N1 (A/FM/1/47) Infectivity In Vitro

Pharmaceuticals, 2017
The influenza virus hemagglutinin (HA) mediates both receptor (glycan) binding and membrane fusion for cell entry and has been the basis for subtyping influenza viruses.
Nataliia Melnichuk, Larisa Semernikova, Zenoviy Tkachuk   +2 more
doaj   +1 more source

Influenza virus activation of the interferon system [PDF]

, 2015
This study was supported by the Wellcome Trust (grant number 087751/A/08/Z) and the Medical Research Council (grant number G0700848).The host interferon (IFN) response represents one of the first barriers that influenza viruses must surmount in order to ...
Fodor, Ervin, Killip, Marian J., Randall, RE, Fodor, E., Killip, MJ, Randall, Richard E., Fodor, E, Killip, M.J., Randall, R.E.   +8 more
core   +1 more source

Serologic Evidence for Influenza C and D Virus among Ruminants and Camelids, Africa, 1991–2015

Emerging Infectious Diseases, 2017
Influenza D virus has been identified in America, Europe, and Asia. We detected influenza D virus antibodies in cattle and small ruminants from North (Morocco) and West (Togo and Benin) Africa.
Elias Salem, Elizabeth A.J. Cook, Hicham Ait Lbacha, Justine Oliva, Félix Awoume, Gilbert L. Aplogan, Emmanuel Couacy Hymann, Dishon Muloi, Sharon L. Deem, Said Alali, Zaid Zouagui, Eric M. Fèvre, Gilles Meyer, Mariette Ducatez   +13 more
doaj   +1 more source

The splicing factor proline-glutamine rich (SFPQ/PSF) is involved in influenza virus transcription. [PDF]

, 2011
The influenza A virus RNA polymerase is a heterotrimeric complex responsible for viral genome transcription and replication in the nucleus of infected cells. We recently carried out a proteomic analysis of purified polymerase expressed in human cells and
Juan Ortín, Landeras-Bueno, Sara, Jorba, N, Sara Landeras-Bueno, Ortín Juan, Pérez-Cidoncha, Maite, Pérez-Cidoncha, M, Núria Jorba, Landeras-Bueno Sara, Pérez-Cidoncha Maite, Landeras-Bueno, S, Ortín, J, Ortín, Juan, Jorba, Núria, Maite Pérez-Cidoncha, Jorba Núria   +15 more
core   +2 more sources

Complexes of Oligoribonucleotides with d-Mannitol Modulate the Innate Immune Response to Influenza A Virus H1N1 (A/FM/1/47) In Vivo

Pharmaceuticals, 2018
Rapid replication of the influenza A virus and lung tissue damage caused by exaggerated pro-inflammatory host immune responses lead to numerous deaths.
Nataliia Melnichuk, Vladimir Kashuba, Svitlana Rybalko, Zenoviy Tkachuk   +3 more
doaj   +1 more source

Serum 25-hydroxyvitamin d level and influenza vaccine immunogenicity in children and adolescents. [PDF]

PLoS ONE, 2014
Vaccination is an important strategy in the prevention of influenza, but immunologic response to vaccination can vary widely. Recent studies have shown an association between serum 25-hydroxyvitamin D (25[OH]D) levels and immune function.
Michelle Science, Jonathon L Maguire, Margaret L Russell, Marek Smieja, Stephen D Walter, Mark Loeb   +5 more
doaj   +1 more source

A novel broad-spectrum treatment for respiratory virus infections : influenza-based defective interfering virus provides protection against pneumovirus infection in vivo [PDF]

, 2011
Respiratory viruses represent a major clinical burden. Few vaccines and antivirals are available, and the rapid appearance of resistant viruses is a cause for concern.
Edworthy, Nicole Lynn, Nicole L. Edworthy, Andrew J. Easton, Meng, Bo, Easton, A. J. (Andrew J.), Bo Meng, Scott, P. D. (Paul D.), Marriott, Anthony C., Anthony C. Marriott, Nigel J. Dimmock, Dimmock, N. J., Paul D. Scott   +11 more
core   +1 more source