Results 191 to 200 of about 124,613 (266)

Black phosphorus‐based photothermal disruption of cancer‐associated fibroblast barriers and tumor‐associated macrophage targeting to enhance anti‐PD‐L1 immunotherapy in triple‐negative breast cancer

Interdisciplinary Medicine, EarlyView.
MBB modulates the TNBC tumor microenvironment by targeting TAM/CXCL1 and facilitates anti‐PD‐L1 therapy by disrupting CAF barriers via its photothermal effect. This combined strategy subsequently enhances the efficacy of PD‐L1 mAb and suppresses TNBC progression, metastasis, and recurrence.
Bo Pan, Shicui Hong, Xinyue Wang, Yanghang Li, Cai Wang, Yaxiao Liu, Ying Chen, Chen Fang, Yifeng Zheng, Shengqi Wang, Juping Zhang, Neng Wang, Zhiyu Wang   +12 more
wiley   +1 more source

Impact of influenza vaccination on in-hospital outcomes among patients with heart failure and acute respiratory illness. [PDF]

Am Heart J Plus
Shafiq A, Javaid SS, Popat A, Asif H, Ahmad M, Ali R, Zaheer I, Arshad U, Jabeen D, Mandokhail AK, Kumar D, Khanam S, Sagar FNU, Usman MS, Hasan A, Ahmed R.   +15 more
europepmc   +1 more source

Targeting eIF5A combats breast cancer progression by ClpP‐dependent mitochondrial oxidative stress

Interdisciplinary Medicine, EarlyView.
This study identified the eIF5A‐ClpP axis as a key driver of breast cancer progression. Targeting eIF5A suppresses tumor growth by inducing ClpP‐dependent mitochondrial oxidative stress, revealing a novel therapeutic vulnerability. Abstract Breast cancer (BC) poses a persistent global health challenge, necessitating new therapeutic targets.
Jinmei Zhu, Baoyuan Tang, Bei Xie, Haohua Deng, Haitang Yang, Lei Ma, Ziqing Zhang, Yicheng Ma, Xingyuan Ma, Shuaiyang Wang, Jing Li, Lei Zhao, Wengui Shi, Linjing Li   +13 more
wiley   +1 more source

The benefits of influenza vaccination in patients with cardiovascular disease: a systematic review and meta-analysis. [PDF]

Front Pharmacol
Wei M, Liu L, Zhou K, Li Y.
europepmc   +1 more source

Maternal influenza vaccination during pregnancy and risk of autism spectrum disorder in the offspring

JCPP Advances, EarlyView.
Abstract Background Vaccination has been proposed as a potential risk factor for autism spectrum disorder (ASD), contributing to public hesitancy and mistrust toward immunization. Influenza vaccination during pregnancy is considered safe and effective in preventing serious maternal complications and adverse birth outcomes associated with influenza ...
Shahar Neeman, Maor Hemo, Gal Meiri, Dorit Shmueli, Idan Menashe   +4 more
wiley   +1 more source

Preexisting IgG forms immune complexes and links local thermal reactogenicity with immunogenicity in influenza vaccination

Hirsiger JR, Scarascia S, Recher M, Bantug G, Berger CT.   +4 more
europepmc   +1 more source

Effectiveness of Maternal Influenza Vaccination on Influenza and Acute Respiratory Infection in Infants. [PDF]

Pediatr Infect Dis J
Homaira N, Qian J, Scaria A, Stepien S, Macartney K, Liu B.   +5 more
europepmc   +1 more source

Trends in hospitalizations for vaccine‐preventable diseases in the United States from 2014 to 2024

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Vaccination rates have declined in recent years, resulting in outbreaks of vaccine‐preventable diseases (VPDs) among children. We aimed to evaluate VPD hospitalization rates from 2014 to 2024 and to report associated trends in outcomes including intensive care utilization, mortality, readmissions, and costs.
Nathan M. Money, Erin Sullivan, Hannah Rector, Corrie E. McDaniel, Jessica L. Markham, Mersine A. Bryan   +5 more
wiley   +1 more source

IFN-gene signatures in B cells following influenza A and B virus infection and influenza vaccination. [PDF]

EMBO Mol Med
Zhang W, Allen EK, Li S, Tarasova I, Farrukee R, Kedzierski L, Gilbertson B, McQuilten HA, Habel JR, Allen LF, Rockman S, Londrigan SL, Kent SJ, Wheatley AK, Trubiano JA, Kotsimbos TC, Cheng AC, Schroeder J, Crawford JC, Thomas PG, Kedzierska K, Nguyen THO.   +21 more
europepmc   +1 more source