Assessment of the variability in influenza A(H1N1) vaccine effectiveness estimates dependent on outcome and methodological approach [PDF]
Estimation of Influenza vaccine effectiveness (VE) varies with study design, clinical outcome 10 considered and statistical methodology used. By estimating VE using differing outcomes and 11 statistical methods on the same cohort of individuals the ...
Kavanagh, Kimberley +2 more
core +5 more sources
Influenza vaccination for immunocompromised patients : systematic review and meta-analysis from a public health policy perspective [PDF]
Background: Immunocompromised patients are vulnerable to severe or complicated influenza infection. Vaccination is widely recommended for this group. This systematic review and meta-analysis assesses influenza vaccination for immunocompromised patients ...
Haroon, Sophie +43 more
core +6 more sources
Effectiveness of influenza vaccine in aging and older adults: comprehensive analysis of the evidence [PDF]
Foremost amongst the diseases preventable by vaccination is influenza. Worldwide, influenza virus infection is associated with serious adverse events leading to hospitalization, debilitating complications, and death in elderly individuals ...
Assir N +11 more
core +1 more source
Cross-sectional survey of older people's views related to influenza vaccine uptake [PDF]
Background The population's views concerning influenza vaccine are important in maintaining high uptake of a vaccine that is required yearly to be effective.
Hanciles, S +23 more
core +2 more sources
Improved adjuvanting of seasonal influenza vaccines: Pre-clinical studies of MVA-NP+M1 co-administration with inactivated influenza vaccine. [PDF]
Licensed seasonal influenza vaccines induce antibody responses against influenza hemagglutinin that are limited in their ability to protect against different strains of influenza.
Gilbert, SC +36 more
core +1 more source
Preferential amplification of CD8 effector-T cells after transcutaneous application of an inactivated influenza vaccine: a randomized phase I trial [PDF]
Background: Current conventional vaccination approaches do not induce potent CD8 T-cell responses for fighting mostly variable viral diseases such as influenza, avian influenza viruses or HIV.
van der Werf, Sylvie +26 more
core +2 more sources
Overview of Serological Techniques for Influenza Vaccine Evaluation: Past, Present and Future [PDF]
Serological techniques commonly used to quantify influenza-specific antibodies include the Haemagglutination Inhibition (HI), Single Radial Haemolysis (SRH) and Virus Neutralization (VN) assays.
Temperton, Nigel J. +12 more
core +1 more source
Age-specific vaccine effectiveness of seasonal 2010/2011 and pandemic influenza A(H1N1) 2009 vaccines in preventing influenza in the United Kingdom [PDF]
An analysis was undertaken to measure age-specific vaccine effectiveness (VE) of 2010/11 trivalent seasonal influenza vaccine (TIV) and monovalent 2009 pandemic influenza vaccine (PIV) administered in 2009/2010.
Ellis, J. +15 more
core +4 more sources
Self-reported adverse reactions in 4337 healthcare workers immunizations against novel H1N1 influenza [PDF]
Purpose: The use of the 2009 H1N1 vaccine has generated much debate concerning safety issues among the general population and physicians. Therefore, we investigated the safety of an inactivated monovalent H1N1 pandemic influenza vaccine Methods: We ...
Harald Bias +15 more
core +1 more source
Stalking influenza by vaccination with pre-fusion headless HA mini-stem. [PDF]
Inaccuracies in prediction of circulating viral strain genotypes and the possibility of novel reassortants causing a pandemic outbreak necessitate the development of an anti-influenza vaccine with increased breadth of protection and potential for rapid ...
Carnell, George +24 more
core +1 more source

