Results 161 to 170 of about 205,975 (308)

Low‐value care and variation in practice in the care of children hospitalized with bronchiolitis in Canada (CareBEST): Protocol for a multi‐center prospective cohort study

Journal of Hospital Medicine, EarlyView.
Abstract Introduction Low‐value care refers to health services for which the potential harms or costs outweigh the benefits of use. Bronchiolitis is the most common and among the most costly causes of pediatric hospitalizations. Evidence consistently shows that many common tests and treatments used to manage bronchiolitis do not improve outcomes ...
Branden Bonham, Tamara Perez, Michelle Bailey, Nick Barrowman, Christopher Bonafide, Ariane Boutin, Melanie Buba, Francine Buchanan, Matthew Carwana, Breanna A. Chen, Evelyn Constantin, Kim de Castris Garcia, Francesca del Giorgio, Zachary Dionisopoulos, Christine Fahim, Karen L. Forbes, Jeremy N. Friedman, Josée Anne Gagnon, Peter J. Gill, Mei Han, Nelly Huynh, Maria Karaceper, Terry P. Klassen, Isabelle Lahaie, Patricia Li, Myla Moretti, Sanjay Mahant, Sarah Manos, Hayat Mekhici, Chris Novak, Olivia Ostrow, Caroline Quach, Julie Quet, Mahmoud Sakran, Anupam Seghal, Alan R. Shroeder, Marc‐André Turcot, Gita Wahi, Olivier Drouin, The Canadian Pediatric Inpatient Research Network (PIRN)   +39 more
wiley   +1 more source

Lysosome-targeting live attenuated influenza vaccines elicit robust and broad immunity in mice. [PDF]

Nat Commun
Hao J, Wang P, Shen Q, Xi X, Tong L, Hou J, Li L, Wang Q, Liu C, Li J, Zhao H, Zhang Q, Plebani R, Chou D, Zhang L, Zhou D, Si L.   +16 more
europepmc   +1 more source

Scheduling early primary care follow‐up after pneumonia: A retrospective target trial emulation in five hospitals

Journal of Hospital Medicine, EarlyView.
Abstract Background Current guidelines make no recommendations on discharge interventions or scheduling outpatient follow‐up after hospitlization for commnity‐acquired pneumonia (CAP). Objectives To assess the impact of scheduling early primary care follow‐up prior to discharge home among survivors of hypoxemic CAP hospitalizations.
Andrew J. Davis, Stephanie P. Taylor, Catherine L. Hough, Mari Armstrong‐Hough, Li Yan, Catherine K. Ettman, Katy Sadowski, Khyzer B. Aziz, Patrick G. Lyons, Katrina E. Hauschildt, Marc Kowalkowski, Eliana M. Perrin, Theodore J. Iwashyna   +12 more
wiley   +1 more source

From methods to policy: a critical appraisal of the 2024 ECDC guidance on enhanced influenza vaccines. [PDF]

Front Public Health
Ortiz de Lejarazu R, Ocaña D, Arrazola P, Orrico-Sánchez A, Redondo E, Sanz-Muñoz I, Tolosa N, Trilla A.   +7 more
europepmc   +1 more source

Trends in hospitalizations for vaccine‐preventable diseases in the United States from 2014 to 2024

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Vaccination rates have declined in recent years, resulting in outbreaks of vaccine‐preventable diseases (VPDs) among children. We aimed to evaluate VPD hospitalization rates from 2014 to 2024 and to report associated trends in outcomes including intensive care utilization, mortality, readmissions, and costs.
Nathan M. Money, Erin Sullivan, Hannah Rector, Corrie E. McDaniel, Jessica L. Markham, Mersine A. Bryan   +5 more
wiley   +1 more source

Shifting Perspective in Influenza Vaccines Efficacy: How Risk Difference Shows an Alternative View of the Comparative Efficacy Profile of Newer and Enhanced Influenza Vaccines Compared to Standard, Egg-Based Vaccines. [PDF]

Vaccines (Basel)
Colombo L, Palache A, Hadigal S.
europepmc   +1 more source

Identification of Clinical Factors Associated With the Immunogenicity of Homologous ChAdOx1‐nCoV‐19 Vaccine in Hemodialysis Patients

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Hemodialysis (HD) patients are at higher risk of severe COVID‐19 and may exhibit suboptimal vaccine responses. This study evaluates the factors influencing vaccine‐induced immunity in HD patients following the second dose of the Vaxzevria. A total of 276 HD patients and 126 controls were included. Antibody responses were assessed using binding
Chia‐Wei Chang, Ping‐Hsun Wu, Li‐Yun Chang, Yu‐Ying Huang, Teng‐Hui Huang, Su‐Chu Lee, Yi‐wen Chiu, Shang‐Jyh Hwang, Tsun‐Yung Kuo, Mei‐Chuan Kuo   +9 more
wiley   +1 more source

Challenges and future perspectives of enhanced passive safety surveillance of influenza vaccines in Europe. [PDF]

Ther Adv Drug Saf
Amaral de Avila Machado M, Gandhi-Banga S, Serradell L, Gallo S, Wagué S, Moore TM, Khromava A.   +6 more
europepmc   +1 more source

Active Learning for the Discovery of Antiviral Polymers

Macromolecular Rapid Communications, EarlyView.
Machine learning and active learning are integrated to accelerate the discovery of antiviral polymers. Molecular descriptors derived from polymer composition enable predictive modeling of antiviral activity, while unsupervised clustering explores chemical diversity. The active learning workflow identifies optimal candidates for synthesis, demonstrating
Clodagh M Boland, Nhat Quynh Nguyen, Nathan RB Boase   +2 more
wiley   +1 more source

Maximizing public health benefits: Policy perspectives on coverage and cell-based influenza vaccines in the US. [PDF]

Hum Vaccin Immunother
Nguyen VH, Mould-Quevedo JF.
europepmc   +1 more source