LL‐37 Inhibits TMPRSS2‐Mediated S2' Site Cleavage and SARS‐CoV‐2 Infection but Not Omicron Variants
Cell Proliferation, EarlyView.Cathelicidin LL‐37 inhibits SARS‐CoV‐2 by blocking the catalytic activity of TMPRSS2. The N764K mutation in the spike S2 subunit of Omicron variants confers resistance to LL‐37‐induced inhibition of TMPRSS2‐mediated S2' priming. ABSTRACT Continual evolution of SARS‐CoV‐2 spike drives the emergence of Omicron variants that show increased spreading and ...
Zhenfei Bi +10 more
wiley +1 more source
Communicating the Value of Influenza Vaccines to Patients. [PDF]
Ann Intern MedTenforde MW, Dawood FS.
europepmc +1 more source
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary The immunosuppressive and immunomodulatory treatment of dermatological patients necessitates the regular review and updating of standard vaccinations and vaccines indicated for specific conditions. The German Standing Committee on Vaccination (STIKO) at the Robert Koch Institute regularly publishes evidence‐based vaccination recommendations ...
Johanna Stoevesandt +3 more
wiley +1 more source
Adults aged 65 years and older in South Africa have a responsibility to vaccinate against influenza
Developing World Bioethics, EarlyView.Abstract In this article, we draw on the thinking about incompleteness and conviviality grounded in Afro‐communitarianism ethics from the Global South to argue that adults aged 65 years and above have a prima facie responsibility to vaccinate against influenza.
Ruach Sarangarajan, Cornelius Ewuoso
wiley +1 more source
Cost-Effectiveness of Adjuvanted Influenza Vaccine Compared with Standard and High-Dose Influenza Vaccines for Persons Aged ≥50 Years in Spain. [PDF]
Vaccines (Basel)Perez-Rubio A +7 more
europepmc +1 more source
What in the world is global health? A conceptual analysis
Developing World Bioethics, EarlyView.Abstract This article suggests that the concept of global health – and to an extent the field that it designates ‐ is problematic in various ways. Within public health, the concept of the ‘public’ has been widely investigated. However, “global health” has been introduced in academic, policy, and public discussion with comparably lower level of ...
Alberto Giubilini
wiley +1 more source
Global Interdependence, Just Vaccine Allocation, and Compensatory Justice: A New Model
Developing World Bioethics, EarlyView.ABSTRACT During the COVID‐19 pandemic, numerous models were offered for how scarce vaccine resources should be distributed. Proposed vaccine distribution models generally were divided between nationalist models, which give preference to nationals, and cosmopolitan models, which ignore national boundaries.
Kalen J. Fredette
wiley +1 more source
Estimated Effectiveness of Influenza Vaccines in Preventing Secondary Infections in Households.
JAMA Netw OpenGrijalva CG +13 more
europepmc +1 more source
A Phase 1/2 Randomized Study to Evaluate the Safety, Tolerability, and Immunogenicity of Nucleoside-Modified Messenger RNA Influenza Vaccines in Healthy Adults. [PDF]
Vaccines (Basel)Branche A +15 more
europepmc +1 more source