Results 131 to 140 of about 2,123,414 (312)

Histone Deacetylase 2 Is a Component of Influenza A Virus-Induced Host Antiviral Response [PDF]

open access: gold, 2017
Prashanth Thevkar Nagesh   +3 more
openalex   +1 more source

Antimicrobial Multi‐Assay Evaluation of (Al‐Doped ZnO)‐Ag and TiO2‐Ag Nanocoatings: Impact of Direct and Indirect Mechanisms

open access: yesAdvanced Materials Interfaces, EarlyView.
This work explores the antimicrobial action of AZO‐Ag and TiO2‐Ag nanocoatings on plastic, demonstrating good efficacy against highly‐critical antibiotic‐resistant bacteria, yeast, and virus. A multi‐assay approach is here exploited to inspect the contribution of direct and indirect antimicrobial mechanisms, and potential human toxicity is also ...
Damiano Squitieri   +10 more
wiley   +1 more source

Functional and Structural Analysis of Influenza Virus Neuraminidase N3 Offers Further Insight into the Mechanisms of Oseltamivir Resistance [PDF]

open access: bronze, 2013
Qing Li   +9 more
openalex   +1 more source

Photonic Crystal Enhanced Microscopy on a 2D Photonic Crystal Surface

open access: yesAdvanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This work demonstrates the design, fabrication, and the first‐time test of a 2D photonic crystal surface for photonic resonator absorption microscopy. The designed surface uniformly enhances electromagnetic near fields, achieving > 100% improved detecting uniformity for surface‐captured AuNPs from a blocking biosensor assay aimed for detecting SARS‐CoV‐
Weinan Liu   +5 more
wiley   +1 more source

Integrin α8‐Mediated Pericyte Morphogenesis Controls Blood‐Brain Barrier Integrity

open access: yesAdvanced Science, EarlyView.
This study highlights that ITGA8 impacts pericyte morphology and function, both crucial for BBB integrity, via RhoA/ROCK signaling, thus influencing TGF‐β1 activation through cytoskeletal tension and ECM interactions. Notably, in post‐ischemic recovery models, ITGA8 deficiency exacerbates vascular dysfunction by impairing pericyte‐mediated BBB ...
Chang‐Xiong Gong   +16 more
wiley   +1 more source

HERV‐K TM Subunit Elicits CD8+ T Cell Anergy and Tumor Immune Evasion via Targeting CD3 Coreceptor ε in AML and PDAC

open access: yesAdvanced Science, EarlyView.
Novel viral immune checkpoint K‐TM subunit is aberrantly expressed in CD8+ T cells and enriched in sera of cancer patients, inducing CD8+ T cell anergy and eliciting potent tumor immune escape in mouse model. Mechanistically, K‐TM directly targets and induces the phosphorylation of CD3ε receptor.
Mengyuan Li   +13 more
wiley   +1 more source

Regular versus Irregular Exercise Differentially Modulates Hippocampal‐Hepatic Acetylcholine Flux to Coordinate Fear Memory Extinction and Liver Inflammation

open access: yesAdvanced Science, EarlyView.
Ma et al. report the hippocampal and hepatic acetylcholine (ACh) levels are differently modulated by regular versus irregular exercise, which contributes to coordinate hippocampal astrocyte activity and hepatic FBXL6high neutrophil recruitment. This ACh‐modulated brain‐liver circuit links the effects of exercise on fear memory extinction and liver ...
Pengjiao Ma   +10 more
wiley   +1 more source

Influenza A Virus Antibodies with Antibody-Dependent Cellular Cytotoxicity Function [PDF]

open access: gold, 2020
Rongyuan Gao   +4 more
openalex   +1 more source

RELA Ablation Contributes to Progression of Hepatocellular Carcinoma with TP53R249S Mutation and is a Potential Therapeutic Target

open access: yesAdvanced Science, EarlyView.
Genome‐wide CRISPR/Cas9 based screening identified RELA as a key tumor suppressor in TP53R249S‐mutant HCC. Its loss promotes tumorigenesis and metastasis via DVL1‐mediated Wnt/β‐catenin activation, while its agonist betulinic acid suppresses tumor progression.
Zhiping Wu   +17 more
wiley   +1 more source

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