Results 161 to 170 of about 343,579 (311)

Determination of relative binding affinity of influenza virus N9 sialidases with the Fab fragment of monoclonal antibody NC41 using biosensor technology [PDF]

, 1993
LC Gruen, Alexander A. Kortt, Edouard C. Nice   +2 more
openalex   +1 more source

Promoting Autophagy Mitigates Stress‐Induced Remodeling in Patient iPSC‐CMs with the Phospholamban R9C Mutation

Advanced Science, EarlyView.
The Phospholamban (PLN) R9C mutation reduces SERCA2a binding, increasing calcium recycling and baseline contractility. However, the excess of free PLN promotes pentamer formation, limiting phosphorylation and blunting β‐adrenergic signaling. Under cardiac stress, enhanced functional demands overwhelm proteostasis in PLN R9C cells, leading to misfolded ...
Qi Yu, Yawei Shen, Robert J. Barndt, Karim Sallam, Ying Tang, Cameron E. Brown, Xiao Li, Stephen Y. Chan, Joseph C. Wu, Qing Liu, Haodi Wu   +10 more
wiley   +1 more source

Dominant substitutions underlying the antigenic evolution of H5 influenza virus. [PDF]

Nat Commun
Zhang M, Qin L, Li Z, Chen J, Tong J, Ding X, Li H, Ma Y, Liu J, He Q, Bi R, Huang W, Bian C, Wang Y, Wu A, Li Q.   +15 more
europepmc   +1 more source

Peptide Inhibitors against Influenza Virus [PDF]

, 2011
Mohamed Rajik, Khatijah Yusoff
openalex   +1 more source

A Eurasian avian-like H1N1 swine influenza reassortant virus became pathogenic and highly transmissible due to mutations in its PA gene

, 2022
Fei Meng, Huanliang Yang, Zhiyuan Qu, Yan Chen, Yijie Zhang, Yaping Zhang, Liling Liu, Xianying Zeng, Chengjun Li, Yoshihiro Kawaoka, Hualan Chen   +10 more
openalex   +2 more sources

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

Advanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu, Yajie Zhang, Yushi Tang, Hongli Hu, Ying Zhang, Junwen Xue, Hao Wang, Yecheng Wang, Chunfeng Liu, Jia Jia, Jian Cheng, Yongjun Cao   +11 more
wiley   +1 more source

Virulence and transmission characteristic of H3N8 avian influenza virus circulating in chickens in China. [PDF]

Virulence
Mei M, Zhang X, Wu Q, Xu M, Zhao Y.
europepmc   +1 more source

Lipid Droplet‐Localized Spindle Apparatus Coiled‐Coil Protein 1 Regulates Lipid Droplet Distribution

Advanced Science, EarlyView.
SPDL1‐L, a long isoform of SPDL1, is identified as a bona fide lipid droplet‐associated protein that acts as a dynein adaptor to drive perinuclear clustering of lipid droplets. By linking lipid droplets to the microtubule network, SPDL1‐L extends the function of SPDL1 beyond mitosis and contributes to lipid droplet organization and nuclear remodeling ...
Honggang Su, Huimin Pan, Yaqiang Liu, Wei Wang, Yang Jiao, Yumo Hang, Xiahe Huang, Yong E. Zhang, Yuhang Chen, Mei Ding, Xun Huang   +10 more
wiley   +1 more source

Development of a portable avian influenza virus characterisation system: bringing the inside-out. [PDF]

Sci Rep
Low YS, Jauregui R, Calcott B, Wilson A, Gias E, Johnston H, Bueno R, Dewar ML, O'Keefe J, McCulley M.   +9 more
europepmc   +1 more source

“Genetic tuning” of avian influenza virus host adaptation from birds to humans

, 2020
Yasuha Arai, Y. Watanabe
openalex   +1 more source