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The neuraminidase of influenza virus
Proteins: Structure, Function, and Bioinformatics, 1989AbstractIt is the enzyme neuraminidase, projecting form the surface of influenza virus particles, which allows the virus to leave infected cells and spread in the body. Antibodies which inhibit the enzyme limit the infection, but antigenic variation of the neuraminidase renders it ineffective in a vaccine.
G M, Air, W G, Laver
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Nature, 1960
THE sialidase of influenza virus has been investigated quantitatively using the method recently described by Warren1 for determining free sialic acid in the presence of the compound bound to muco-protein substrates. For this work, the substrate used was a mucoid derived from the nest-cementing substance of the swiftlet (Collocalia sp.).
C, HOWE, L T, LEE, H M, ROSE
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THE sialidase of influenza virus has been investigated quantitatively using the method recently described by Warren1 for determining free sialic acid in the presence of the compound bound to muco-protein substrates. For this work, the substrate used was a mucoid derived from the nest-cementing substance of the swiftlet (Collocalia sp.).
C, HOWE, L T, LEE, H M, ROSE
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Biologicals, 1995
The establishment of reverse genetics methods to manipulate influenza virus genomes has allowed the generation of recombinant (transfectant) influenza viruses expressing foreign sequences. Strategies for the construction of influenza virus vectors include the insertion of foreign epitopes into influenza virus glycoproteins, the expression of ...
A, García-Sastre, P, Palese
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The establishment of reverse genetics methods to manipulate influenza virus genomes has allowed the generation of recombinant (transfectant) influenza viruses expressing foreign sequences. Strategies for the construction of influenza virus vectors include the insertion of foreign epitopes into influenza virus glycoproteins, the expression of ...
A, García-Sastre, P, Palese
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Hemagglutination by Influenza Virus: III. The Xo Phase of Influenza A Virus
Journal of Infectious Diseases, 1948In the original characterization of the O-D change in influenza virus, type A, Burnet and Bull1 stated that they found no evidence of a change from the D to the O phase, but that the O phase could be transformed by a process of discontinuous mutation to the D phase.
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2012
The isolation of influenza viruses is important for the diagnosis of respiratory diseases in lower animals and humans, for the detection of the infecting agent in surveillance programs, and is an essential element in the development and production of vaccine.
Scott, Krauss +2 more
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The isolation of influenza viruses is important for the diagnosis of respiratory diseases in lower animals and humans, for the detection of the infecting agent in surveillance programs, and is an essential element in the development and production of vaccine.
Scott, Krauss +2 more
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Comparative Immunology, Microbiology and Infectious Diseases, 2009
Avian influenza viruses do not typically replicate efficiently in humans, indicating direct transmission of avian influenza virus to humans is unlikely. However, since 1997, several cases of human infections with different subtypes (H5N1, H7N7, and H9N2) of avian influenza viruses have been identified and raised the pandemic potential of avian ...
Chang-Won, Lee, Yehia M, Saif
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Avian influenza viruses do not typically replicate efficiently in humans, indicating direct transmission of avian influenza virus to humans is unlikely. However, since 1997, several cases of human infections with different subtypes (H5N1, H7N7, and H9N2) of avian influenza viruses have been identified and raised the pandemic potential of avian ...
Chang-Won, Lee, Yehia M, Saif
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2012
The laboratory diagnosis of influenza uses a wide range of techniques including rapid immunoassays, immunofluorescence techniques, virus culture methods, and increasingly sophisticated molecular assays. The potential utility of each of these methods has changed over the years, most dramatically perhaps with the emergence of the pandemic H1N1 2009 ...
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The laboratory diagnosis of influenza uses a wide range of techniques including rapid immunoassays, immunofluorescence techniques, virus culture methods, and increasingly sophisticated molecular assays. The potential utility of each of these methods has changed over the years, most dramatically perhaps with the emergence of the pandemic H1N1 2009 ...
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Canadian Journal of Research, 1947
Influenza A and B viruses in allantoic fluid can be adsorbed by certain grades of diatomaceous earths usually employed as filter aids, there being a marked degree of correlation between the 'flow rate' of the earths and their ability to adsorb the virus.
R, HARE, M, CURL
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Influenza A and B viruses in allantoic fluid can be adsorbed by certain grades of diatomaceous earths usually employed as filter aids, there being a marked degree of correlation between the 'flow rate' of the earths and their ability to adsorb the virus.
R, HARE, M, CURL
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The Journal of Immunology, 1951
Summary The production of nontoxic influenza A virus has been described. This was accomplished by inoculating undiluted, non-mouse-adapted, allantoic fluid virus into the allantoic sac of the developing chick embryo. Mouse-adapted influenza virus would not cause nontoxic virus to be produced.
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Summary The production of nontoxic influenza A virus has been described. This was accomplished by inoculating undiluted, non-mouse-adapted, allantoic fluid virus into the allantoic sac of the developing chick embryo. Mouse-adapted influenza virus would not cause nontoxic virus to be produced.
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Influenza A Virus Reassortment
2014Reassortment is the process by which influenza viruses swap gene segments. This genetic exchange is possible due to the segmented nature of the viral genome and occurs when two differing influenza viruses co-infect a cell. The viral diversity generated through reassortment is vast and plays an important role in the evolution of influenza viruses ...
John, Steel, Anice C, Lowen
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