Results 211 to 220 of about 2,123,414 (312)

Structural basis of influenza virus fusion inhibition by the antiviral drug Arbidol

Proceedings of the National Academy of Sciences of the United States of America, 2016
R. Kadam, I. Wilson
semanticscholar   +1 more source

Multimodal Imaging Reveals Cerebral Microcirculation Dynamics and Mechanisms in Mouse Central Nervous System After Intranasal Infection With Recombinant Pseudorabies Virus

Advanced Science, EarlyView.
Multi‐modality imaging strategy applied to PRV‐induced central nervous system infection enables dynamic visualization of cerebrovascular dysfunction, including hyperemia, hypoperfusion, and vascular remodeling. These changes are linked to microglial activation and impaired angiogenesis, providing mechanistic insight into PRV neuropathogenesis and ...
Shuting Ling, Chongxin Wu, Mengxuan Gui, Kaiyun Chen, Yanbo Yang, Jiwei Xing, Fengxian Du, Wei Liao, Luyao Yang, Zhaokui Jin, Ningshao Xia, Guosong Wang, Yixin Chen, Qingliang Zhao   +13 more
wiley   +1 more source

Loss of Dmrta1 alters CD8+ T cell activation and resistance to influenza virus infection. [PDF]

Immunohorizons
Kondo H, Otsuka K, Morimoto J, Arimochi H, Tsukumo SI, Yasutomo K.   +5 more
europepmc   +1 more source

Phylogenetic Insights into H7Nx Influenza Viruses: Uncovering Reassortment Patterns and Geographic Variability

Sofya G. Feoktistova, A. S. Ivanova, Egor P. Degtyarev, D. I. Smirnova, Pavel Volchkov, Andrei A. Deviatkin   +5 more
openalex   +1 more source

Resident memory CD8+ T cells in the upper respiratory tract prevent pulmonary influenza virus infection

Science immunology, 2017
A. Pizzolla, Thi H. O. Nguyen, Jeffrey M. Smith, A. Brooks, K. Kedzierska, W. Heath, P. Reading, L. Wakim   +7 more
semanticscholar   +1 more source

Single‐Cell RNA Sequencing of Thyroid Tissues Reveals Pathogenesis of Graves' Disease

Advanced Science, EarlyView.
Using single‐cell RNA sequencing and TCR profiling, this study constructed an immune cell atlas in thyroid tissue of Graves’ disease (GD), revealing dominant IFN‐γ‐secreting CD4+ T cells, expanded Tph and CD11c+ B cells, and enriched T/NK cells. Notably, GD thyroid follicular cells (TFCs) activated γδ T cells, which recruited cDC1 cells, suggesting a ...
Xiaoyi Zhou, Jia Cong, Rongguang Peng, Dichen Yang, Chenchen Dong, Jing Xie, Jiqi Yan, Jie Kuang, Fubin Li, Leng Siew Yeap, Xiaoyan Xie, Haolong Yin, Rulai Han, Liyun Shen, Yulin Zhou, Guang Ning, Shu Wang, Weiqing Wang, Lei Ye   +18 more
wiley   +1 more source

Comparative evaluation of different transport media for H5N1 highly pathogenic avian influenza virus. [PDF]

Sci Rep
Dixit B, Murugkar HV, Nagarajan S, Kumar M, Anjay A, Dixit M, Shrivastav A, Jha AK, Mishra AK, Singh RV, Tosh C.   +10 more
europepmc   +1 more source

I222 Neuraminidase Mutations Further Reduce Oseltamivir Susceptibility of Indonesian Clade 2.1 Highly Pathogenic Avian Influenza A(H5N1) Viruses

, 2013
Jennifer L. McKimm‐Breschkin, Susan Barrett, Pudjiatmoko, Muhammad Azhar, Frank Wong, Paul Selleck, Peter G. Mohr, James McGrane, Mia Kim   +8 more
openalex   +2 more sources

HPD is an m6A Methyltransferase that Protects Colorectal Cancer Cells from Ferroptotic Cell Death by m6A Methylating SLC7A11/GPX4

Advanced Science, EarlyView.
This study reveals that the tyrosine metabolic enzyme HPD functions as a previously uncharacterized, METTL3‐independent m6A methyltransferase. It promotes colorectal tumor progression by coordinately regulating the SLC7A11/GPX4 axis to suppress ferroptosis.
Jiyan Wang, Xintong Dai, Huanle Liu, Saiwei Hua, Hongkai Chang, Huanran Sun, Mingming Sun, Huifang Zhao, Kemin Ni, Fei Xie, Yaya Qiao, Qingle Gao, Chenxi Yu, Qijun Zhang, Jianshuang Guo, Chunze Zhang, Shuai Zhang, Changliang Shan   +17 more
wiley   +1 more source

Discovery of a novel broad-spectrum inhibitor against influenza virus A. [PDF]

Virol J
Yu R, Li P, Shen R, Fei W.
europepmc   +1 more source