Results 191 to 200 of about 1,140,283 (405)

Structural and Biochemical Characterization of a Widespread Enterobacterial Peroxidase Encapsulin

open access: yesAdvanced Science, EarlyView.
Encapsulins are self‐assembling bacterial protein compartments loaded with cargo enzymes. The most abundant encapsulin cargo class are Dye‐decolorizing Peroxidases (DyPs). In this study, we structurally and biochemically characterize a DyP encapsulin found in many enterobacteria.
Natalia C. Ubilla‐Rodriguez   +2 more
wiley   +1 more source

Non‐Invasive Tumor Budding Evaluation and Correlation with Treatment Response in Bladder Cancer: A Multi‐Center Cohort Study

open access: yesAdvanced Science, EarlyView.
This study introduces a deep learning model that predicts tumor budding (TB) status in bladder cancer through the analysis of CT images. The model effectively identifies patients with high TB status, correlating with poorer prognosis and reduced responsiveness to neoadjuvant chemoimmunotherapy. This tool offers significant potential to inform prognosis
Xiaoyang Li   +21 more
wiley   +1 more source

Decoding MIE: A Novel Dataset Approach Using Topic Extraction and Affiliation Parsing [PDF]

open access: yesarXiv
The rapid expansion of medical informatics literature presents significant challenges in synthesizing and analyzing research trends. This study introduces a novel dataset derived from the Medical Informatics Europe (MIE) Conference proceedings, addressing the need for sophisticated analytical tools in the field.
arxiv  

Trustworthy Inverse Molecular Design via Alignment with Molecular Dynamics

open access: yesAdvanced Science, EarlyView.
Data‐driven inverse molecular design (IMD) is a promising approach to discovering new molecules with desired properties. Despite the remarkable progress, existing IMD methods lag behind in terms of trustworthiness, as indicated by their misalignment with the ground‐truth function that models the molecular dynamics.
Kevin Tirta Wijaya   +3 more
wiley   +1 more source

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