Results 291 to 300 of about 518,037 (342)

Loneliness, social isolation, and effects on cognitive decline in patients with dementia: A retrospective cohort study using natural language processing. [PDF]

Alzheimers Dement (Amst)
Myers JAC, Stafford T, Koychev I, Perneczky R, Bandmann O, Vaci N.   +5 more
europepmc   +1 more source

CYP2C19 Polymorphisms and Clinical Outcomes Following Percutaneous Coronary Intervention in the Million Veteran Program

Clinical Pharmacology &Therapeutics, EarlyView.
CYP2C19 loss‐of‐function (LOF) alleles decrease the antiplatelet effect of clopidogrel following percutaneous coronary intervention (PCI) in patients presenting with acute coronary syndrome (ACS). The impact of genotype in patients undergoing PCI for stable ischemic heart disease (SIHD) in real‐world populations is less clear.
Catherine Chanfreau‐Coffinier, Kevin A. Friede, Mary E. Plomondon, Kyung Min Lee, Zhenyu Lu, Tia Dinatale, Scott L. DuVall, Jason L. Vassy, Stephen W. Waldo, John H. Cleator, Thomas M. Maddox, Daniel J. Rader, Themistocles L. Assimes, Scott M. Damrauer, Philip S. Tsao, Kyong‐Mi Chang, Deepak Voora, Julie A. Lynch, Jay Giri, VA Million Veteran Program, Sony Tuteja   +20 more
wiley   +1 more source

Unlocking efficiency in real-world collaborative studies: a multi-site international study with one-shot lossless GLMM algorithm. [PDF]

NPJ Digit Med
Tong J, Reps JM, Luo C, Lu Y, Li L, Ramirez-Anguita JM, Brand MT, DuVall SL, Falconer T, Fuentes AM, He X, Matheny ME, Mayer MA, Patel BK, Simon KR, Suchard MA, Tang G, Viernes B, Williams RD, van Zandt M, Wang F, Bian J, Zhou J, Asch DA, Chen Y.   +24 more
europepmc   +1 more source

Impact of First‐of‐Its‐Kind Patient‐Facing Pharmacogenetics Tool on Dosing Decisions and Treatment Outcomes

Clinical Pharmacology &Therapeutics, EarlyView.
Germline pharmacogenetics (PGx) is increasingly used to tailor medication selection/dosing. However, existing systems primarily communicate PGx results to providers, limiting direct patient engagement. To address this, we developed YourPGx Oncology, an innovative patient‐facing portal that delivers multi‐gene PGx results (CYP2D6, UGT1A1, DPYD) through ...
Youngwoo Cho, Sami Elahi, Matthew M. Jack, John Campbell, Emily Smith, Randall W. Knoebel, David George, Larry House, Kiang‐Teck J. Yeo, Theodore Karrison, Samuel L. Volchenboum, David O. Meltzer, Russell Z. Szmulewitz, Everett E. Vokes, Mark J. Ratain, Peter H. O'Donnell   +15 more
wiley   +1 more source

Correction: Checklist for Reproducibility of Deep Learning in Medical Imaging. [PDF]

J Imaging Inform Med
Moassefi M, Singh Y, Conte GM, Khosravi B, Rouzrokh P, Vahdati S, Safdar N, Moy L, Kitamura F, Gentili A, Lakhani P, Kottler N, Halabi SS, Yacoub JH, Hou Y, Younis K, Erickson BJ, Krupinski E, Faghani S.   +18 more
europepmc   +1 more source

Understanding the evidence for artificial intelligence in healthcare. [PDF]

BMJ Qual Saf
Jackson GP, Shortliffe EH.
europepmc   +1 more source

Retraction: "A Dynamic Adaptive Ensemble Learning Framework for Noninvasive Mild Cognitive Impairment Detection: Development and Validation Study".

JMIR Med Inform
JMIR Editorial Office.
europepmc   +1 more source

Correction to: Risk factors associated with unplanned readmissions and frequent out-of-hour emergency department visits after pediatric tracheostomy: a nationwide inpatient database study in Japan. [PDF]

Eur J Pediatr
Ito-Shinjo A, Shinjo D, Nakamura T, Kubota M, Fushimi K.   +4 more
europepmc   +1 more source

Vaccination Schedules Recommended by the Centers for Disease Control and Prevention: From Human-Readable to Machine-Processable. [PDF]

Vaccines (Basel)
Jing X, Min H, Gong Y, Ernst MA, Weaver A, Crozier C, Robinson D, Sittig DF, Biondich PG, Orlioglu S, Shanmugan Boobalan A, Abanyie K, Boyce RD, Wright A, Nøhr C, Law TD, Faxvaag A, Rennert L, Gimbel RW.   +18 more
europepmc   +1 more source

Leveraging Interoperable Electronic Health Record (EHR) Data for Distributed Analyses in Clinical Research: Technical Implementation Report of the HELP Study.

JMIR Med Inform
Palm J, Saleh K, Scherag A, Ammon D.
europepmc   +1 more source