Results 41 to 50 of about 845,536 (289)
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
A Multifunctional, Low Cost and Sustainable Neonatal Database System
ChildrenContinuous improvement in the clinical performance of neonatal intensive care units (NICU) depends on the use of locally relevant, reliable data. However, neonatal databases with these characteristics are typically unavailable in NICUs using paper-based ...
Joaquim M. B. Pinheiro +14 more
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PRINCIPLES, BASES, AND LAWS OF FUNDAMENTAL INFORMATICS
Открытое образование (Москва), 2016 This paper defines the goals and problems of fundamental informatics, formulates principal laws of information universe and constructive bases of information objects and processes.
Gennady N. Zverev
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, 1999 This symposium was held in Washington, DC in November 1999.The AMIA Annual Symposium program emphasizes an integrated view of informatics and is organized around four cornerstone areas: Representing Knowledge, Acquiring and Presenting Data, Managing ...
American Medical Informatics Association
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Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
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Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Informatics, 2013 On being promoted to a personal chair in 1993 I chose the title of Professor of Informatics, specifically acknowledging Donna Haraway’s definition of the term as the “technologies of information [and communication] as well as the biological, social, linguistic and cultural changes that initiate, accompany and complicate their development” [1].
openaire +4 more sources
FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
Informatics in the UK: Current Perspectives
, 2007 Computing, Computer Science and Information Science are the nearest UK equivalents of the European Informatics degree. Informatics is a term more often associated with research or multidisciplinary applications of Computing.
Irons, Alastair, White, Su
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Geriatric Telemedicine: Background and Evidence for Telemedicine as a Way to Address the Challenges of Geriatrics [PDF]
Healthcare Informatics Research, 2015 ObjectivesThe global population of elderly people is increasing at a remarkable rate, which may be expected to continue for some time. Older patients require more care, and with the current model of care delivery, the costs may be expected to rise ...
Ronald C. Merrell
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