Results 141 to 150 of about 53,551 (305)

Mini-ccnx: Fast Prototyping For Named Data Networking

open access: yes, 2015
Experimental research in Information-Centric Networking (ICN) is crucial to the evaluation of new architectural proposals that bring named pieces of content as the main element of networks.
Magalhaes M.F.   +2 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Modeling and Evaluating a Cache System in ICN Routers Using a Programmable Switch and Computers

open access: yesIEEE Access
Information-centric networking (ICN) is one of promising networking architectures to replace IP because its notable feature, in-network caching, is expected to reduce about a one-third of the forever increasing Internet traffic. However, the existing ICN
Junji Takemasa   +2 more
doaj   +1 more source

Networking at Information Centric Edge [PDF]

open access: yes, 2019
More and more heterogeneous devices are getting connected to the Internet, leading us to the era of Internet of Things. However, this trend is hardly sustainable under today's Internet, because of the inefficiency of IP networking for user information ...
Zhao, Tao
core  

Information-Centric Networking

open access: yes, 2012
This paper reviews the proposals related to Information centric networks, which is a new emerging research area. This paper also discusses some of the most prevailing challenges that scientists face.
Mathieu, Bertrand   +4 more
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

CONET: A Content Centric Inter-Networking Architecture

open access: yes, 2011
CONET is a content-centric inter-network that provides users with a network access to remote named-resources, rather than to remote hosts. Named-resources can be either data (named-data) or service-access-points (named-sap), identified by a network ...
Matteo Pomposini   +11 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

A Blockchain Network Communication Architecture Based on Information-Centric Networking

open access: yesApplied Sciences
Blockchain technology, as a distributed ledger technology, is becoming increasingly popular in various fields. However, the performance limitations of blockchain networks hinder their further development.
Yufei Zhou, Rui Han, Yang Li
doaj   +1 more source

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