Results 101 to 110 of about 2,801,125 (306)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Do Parties Matter for Fiscal Policy Choices? A Regression-Discontinuity Approach [PDF]
This paper presents a method for measuring the causal effect of party control on fiscal policy outcomes. The source of identifying information comes from an institutional feature of the election system, namely that party control changes discontinuously ...
Pettersson-Lidbom , Per
core
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
MODERN ARCHITECTURE BOARD INFORMATION AND CONTROL SYSTEMS OF HEAVY VEHICLES
Российский технологический журнал, 2017 The continuous increase in amounts of data processed on board of modern heavy trucks and complication of onboard systems and units functioning algorithms have led to the need to transfer the functions performed by a motorist to automatic robotized ...
A. Z. Asanov
doaj +1 more source
Instrumentation and automation system defects detection [PDF]
, 2014 EN: This paper presents the methodology used for the automation of a mechatronic system, which will be used for information of teeth, the work was done using a microcontroller, which allows the reconfiguration of the system, the use of different ports ...
Aguilar Rodriguez, M. +7 more
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Simulation Model of Information-Measuring and Control System [PDF]
Izvestiâ vysših učebnyh zavedenij. Priborostroenie, 2015 Yu.Yu. Gatchina, O.F. Nemolochnov
openaire +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Автоматизированная информационно-измерительная система квалиметрического контроля [PDF]
, 2013 Использование АСНК при непрерывно действующей системе оценки качества приводит к ряду особенностей в оценивании неопределенности экспертных оценок, с помощью которых осуществляется проверка, а также в оценке роли этих неопределенностей в оценке качества ...
Дроздова, Т.В. +1 more
core