Results 111 to 120 of about 2,801,125 (306)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Improving the accuracy of measurement of electrical values in the networks of regional energy companies

Вісник Національного технічного університету "ХПÌ". Енергетика: надійність та енергоефективність
The article considers the issues of increasing the accuracy and reliability of measurements of electrical quantities in the field of electric power. The high-voltage measuring path consists of current, voltage transformers and measuring devices.
Ігор Васильович Хоменко, Віктор Сергійович Орлов, Михайло Володимирович Карпушин, Святослав Олександрович Рябінін   +3 more
doaj   +1 more source

Information flows management in logistic system of a trading industrial enterprise [PDF]

, 2016
Проаналізовано існуючі підходи до побудови логістичної системи та логістичної інформаційної системи. Розглянуто структуру логістичної інформаційної системи та виділено можливі матеріальні, фінансові й інформаційні потоки в логістичній системі торговельно-
Tril, Hryhoriy, Тріль, Григорій Миколайович   +1 more
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

First proof of concept of remote attendance for future observation strategies between Wettzell (Germany) and Concepción (Chile) [PDF]

, 2010
Current VLBI observations are controlled and attended locally at the radio telescopes on the basis of pre-scheduled session files. Operations have to deal with system specific station commands and individual setup procedures.
Dassing, R, Ettl, Martin, Hase, H, Herrera, C, Mühlbauer, M, Neidhardt, Alexander, Oñate, E, Plötz, C, Sobarzo, S, Zaror, P   +9 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Information-measuring system of control of the normalized parameters of industrial factors

Eastern-European Journal of Enterprise Technologies, 2014
В роботі представлені результати досліджень по створенню інформаційно-вимірювальної системи контролю нормованих параметрів промислових факторів. Проведено комп'ютерне моделювання датчиків та їх вимірювальних кіл з метою дослідження процесів, що в них протікають, оптимізації параметрів та покращення характеристик. Наведені результати контролю виробничих
openaire   +4 more sources

ENSURING THE EFFICIENCY OF INFORMATION-MEASURING AND CONTROL SYSTEMS

Measuring. Monitoring. Management. Control, 2020
O. E. Bezborodova, O. N. Bodin, M. N. Kramm, V. V. Sherstnev   +3 more
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

The Effect of Music Therapy on Patients' Blood Pressure in Endoscopy Unit in Bou-Ali hospital, Ardebil [PDF]

Today, endoscopic evaluation of digestive system is an important diagnostic approach in gastrointestinal diseases. As it is an invasive method, it causes fear and anxiety in patients.
امانی, فیروز, تذکری, زهرا, کریم اللهی, منصوره   +2 more
core