Results 101 to 110 of about 3,610,646 (298)

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Flight array processor [PDF]

open access: yes
Spaceflight applications for the NASA Scatterometer (NSCAT) , an ocean surface wind measuring system flown as part of the Navy Remote Ocean Sensing System (NROSS) are discussed in outline form, along with information on the Advanced Digital Synthetic ...

core   +1 more source

High Resolution Current & Bathymetry Determined by Nautical X-Band Radar in Shallow Waters [PDF]

open access: yes, 2009
The wave and current monitoring system WaMoS II is a remote sensing system based on a nautical X-Band radar generally used for navigation and ship traffic control.
Bell, Paul S., Hessner, Katrin
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

INFORMATION-MEASURING SYSTEMS FOR ELECTRICAL PROPULSION UNIT

open access: yesJournal of Rocket-Space Technology, 2019
Considered electric propulsion systems (EPS) based on the Hall effect. Structure of EPS includes hall thruster (HT), xenon feed system (XFS), power processing unit and automatic control and monitoring system. The task is to design information-measuring system (IMS), which allows measurement of the current settings of EPS, conduct their mathematical ...
Sergey Aleksandrovich Pletin   +1 more
openaire   +2 more sources

The Cost Impact of Spam Filters: Measuring the Effect of Information System Technologies in Organizations [PDF]

open access: yes
More than 70% of global e-mail traffic consists of unsolicited and commercial direct marketing, also known as spam. Dealing with spam incurs high costs for organizations, prompting efforts to try to reduce spam-related costs by installing spam filters ...
Caliendo, Marco   +3 more
core  

Multiple-sensor integration for efficient reverse engineering of geometry [PDF]

open access: yes, 2013
This paper describes a multi-sensor measuring system for reverse engineering applications. A sphere-plate artefact is developed for data unification of the hybrid system.
Fletcher, Simon   +3 more
core  

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Fiber-optic system for measuring temperature of rigid deformable media

open access: yesИзвестия высших учебных заведений. Поволжский регион:Технические науки
Background. Currently, during the construction of new nuclear power plants (NPP), its service life has been extended to 60 years, which requires the modernization of information and measurement systems that control many parameters of the dome of the ...
T.I. Murashkina   +4 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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