Results 191 to 200 of about 3,610,646 (298)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Metabolic rate measurements of two benthic invertebrates under simulated climate change conditions. [PDF]

Biodivers Data J
Grigoriou P, Chatzinikolaou E, Anastasiadis A, Papandroulakis N, Stavrakidis-Zachou O, Dailianis T.   +5 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

An instrument for measuring the influence of nursing care on the length of stay in heart failure hospitalizations of African Americans. [PDF]

J Clin Transl Sci
Williams TB, Bimali M, Parker P, Crump A, Seker E, Garza MY, Greer M, Massey-Swindle T, Sexton KW.   +8 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Using wavelet decomposition to determine the dimension of structures from projected images. [PDF]

Proc Natl Acad Sci U S A
Mayboroda S, Spergel DN.
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

General scales unlock AI evaluation with explanatory and predictive power. [PDF]

Nature
Zhou L, Pacchiardi L, Martínez-Plumed F, Collins KM, Moros-Daval Y, Zhang S, Zhao Q, Huang Y, Sun L, Prunty JE, Li Z, Sánchez-García P, Jiang-Chen K, Casares PAM, Zu J, Burden J, Mehrbakhsh B, Stillwell D, Cebrian M, Wang J, Henderson P, Wu ST, Kyllonen PC, Cheke L, Xie X, Hernández-Orallo J.   +25 more
europepmc   +1 more source

ANALYSIS OF THE INFORMATION-MEASURING SYSTEM OF MECHANICAL MOMENTS

Reliability & Quality of Complex Systems, 2017
V. Ya. Goryachev, S. V. Kislyakov, Т. Yu. Brostilova   +2 more
openaire   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source