Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Mechanism for credibility assessment of online health information by medical students in the digital-intelligent age-a grounded theory study in China. [PDF]
Jiang Y +5 more
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
No Evidence for Curiosity-Driven Information Selection Advantage in Infants' Novel Word Learning. [PDF]
Bazhydai M +4 more
europepmc +1 more source
Study of Query Expansion Techniques and Their Application in the Biomedical Information Retrieval [PDF]
Aurea Rivas, Eva Iglesias, L. Borrajo
openalex +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
The Hierarchical Disentangled Information framework enables the discovery of meaningful structures. [PDF]
Hasanabadi MR, Gharavian D.
europepmc +1 more source
Information criteria for Firth's penalized partial likelihood approach in Cox regression models [PDF]
Kengo Nagashima, Yasunori Sato
openalex +1 more source
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
6G -enabled qubit-based concealed communication with AI-driven breach detection in autonomous fleets. [PDF]
T V +3 more
europepmc +1 more source

